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ISHC Hands-On VM
In Silico Hepatocyte Culture hands-on demonstration. A user can download this Virtual Box VM, run it in their local Virtual Box installation and play with the ISHC.
ISHC VM
Oct 14, 2014

Virtual Box VM for running the ISHC.  View License

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Oct 14, 2014
571 MB
Any
Application/binary
ISHC VirtualBox VM.

PLEASE CITE THESE PAPERS

Petersen et al. (2014) Toward modular biological models: defining analog modules based on referent physiological mechanisms (2014) View


ISLJ ALT release MM
The In Silico Liver software system used to test Model Mechanisms for ALT released on Acetaminophen hepatotoxicity.
ISLJ ALT MM v1198
Nov 08, 2019

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Nov 08, 2019
23 MB
Any
Data/images/video
The In Silico Liver software system used to test Model Mechanisms for ALT released on Acetaminophen hepatotoxicity.

Nov 08, 2019
2 MB
Any
Data/images/video
Parameter files for the ALT release Model Mechanisms: Necrosis-Model, nonMD-Model, MitoD-Model, and Dual-Model.

Nov 12, 2019
93 MB
Any
Data/images/video
Results of all experiments on the Model Mechanism variants of ALT release from AILI used in the ALT MS are here


ISLJ Hepatic Neighbors
This package contains the ISLJ source code as well as instructions to run experiments as described in the manuscript.
islj-hepn-1169
Jan 07, 2019

Notes  View License

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Jan 07, 2019
18 MB
Any
Source code
ISLJ source code along with instructions on running experiments described in the manuscript.


ISLJ in vitro-to-in vivo
This package contains the ISLJ source code as well as instructions to run experiments as described in the manuscript.
islj, svn revision 1352
Sep 30, 2021

Notes  View License

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Sep 30, 2021
23 MB
Linux
Source code
This package contains the ISLJ source code as well as instructions to run experiments as described in the manuscript. To extract the files, run a command like: "tar -xvzf islj.tgz" Next, navigate to the islj directory and open the README file for further instructions.

PLEASE CITE THESE PAPERS

Utilizing virtual experiments to increase understanding of discrepancies involving in vitro-to-in vivo predictions of hepatic clearance (2021)


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