<html xmlns:v="urn:schemas-microsoft-com:vml" xmlns:o="urn:schemas-microsoft-com:office:office" xmlns:w="urn:schemas-microsoft-com:office:word" xmlns:m="http://schemas.microsoft.com/office/2004/12/omml" xmlns="http://www.w3.org/TR/REC-html40"><head><META HTTP-EQUIV="Content-Type" CONTENT="text/html; charset=us-ascii"><meta name=Generator content="Microsoft Word 12 (filtered medium)"><style><!--
/* Font Definitions */
@font-face
{font-family:"Cambria Math";
panose-1:2 4 5 3 5 4 6 3 2 4;}
@font-face
{font-family:Calibri;
panose-1:2 15 5 2 2 2 4 3 2 4;}
/* Style Definitions */
p.MsoNormal, li.MsoNormal, div.MsoNormal
{margin:0in;
margin-bottom:.0001pt;
font-size:11.0pt;
font-family:"Calibri","sans-serif";}
a:link, span.MsoHyperlink
{mso-style-priority:99;
color:blue;
text-decoration:underline;}
a:visited, span.MsoHyperlinkFollowed
{mso-style-priority:99;
color:purple;
text-decoration:underline;}
p.MsoListParagraph, li.MsoListParagraph, div.MsoListParagraph
{mso-style-priority:34;
margin-top:0in;
margin-right:0in;
margin-bottom:0in;
margin-left:.5in;
margin-bottom:.0001pt;
font-size:11.0pt;
font-family:"Calibri","sans-serif";}
span.EmailStyle17
{mso-style-type:personal-compose;
font-family:"Calibri","sans-serif";
color:windowtext;}
.MsoChpDefault
{mso-style-type:export-only;}
@page WordSection1
{size:8.5in 11.0in;
margin:1.0in 1.0in 1.0in 1.0in;}
div.WordSection1
{page:WordSection1;}
/* List Definitions */
@list l0
{mso-list-id:492382279;
mso-list-type:hybrid;
mso-list-template-ids:-464333340 67567617 67567619 67567621 67567617 67567619 67567621 67567617 67567619 67567621;}
@list l0:level1
{mso-level-number-format:bullet;
mso-level-text:\F0B7;
mso-level-tab-stop:none;
mso-level-number-position:left;
text-indent:-.25in;
font-family:Symbol;}
@list l0:level2
{mso-level-tab-stop:1.0in;
mso-level-number-position:left;
text-indent:-.25in;}
@list l0:level3
{mso-level-tab-stop:1.5in;
mso-level-number-position:left;
text-indent:-.25in;}
@list l0:level4
{mso-level-tab-stop:2.0in;
mso-level-number-position:left;
text-indent:-.25in;}
@list l0:level5
{mso-level-tab-stop:2.5in;
mso-level-number-position:left;
text-indent:-.25in;}
@list l0:level6
{mso-level-tab-stop:3.0in;
mso-level-number-position:left;
text-indent:-.25in;}
@list l0:level7
{mso-level-tab-stop:3.5in;
mso-level-number-position:left;
text-indent:-.25in;}
@list l0:level8
{mso-level-tab-stop:4.0in;
mso-level-number-position:left;
text-indent:-.25in;}
@list l0:level9
{mso-level-tab-stop:4.5in;
mso-level-number-position:left;
text-indent:-.25in;}
ol
{margin-bottom:0in;}
ul
{margin-bottom:0in;}
--></style><!--[if gte mso 9]><xml>
<o:shapedefaults v:ext="edit" spidmax="1026" />
</xml><![endif]--><!--[if gte mso 9]><xml>
<o:shapelayout v:ext="edit">
<o:idmap v:ext="edit" data="1" />
</o:shapelayout></xml><![endif]--></head><body lang=EN-US link=blue vlink=purple><div class=WordSection1><p class=MsoNormal><b><span style='font-size:14.0pt;font-family:"Arial","sans-serif"'>Webinar: Assessing Clinical and Economic Benefits of Biocomputational Models. A Case Study with Physiome Models</span></b><b><span style='font-size:18.0pt;font-family:"Arial","sans-serif"'> <o:p></o:p></span></b></p><p class=MsoNormal><span style='font-size:12.0pt;font-family:"Arial","sans-serif"'><o:p> </o:p></span></p><p class=MsoNormal><span style='font-family:"Arial","sans-serif"'>Karl Stroetmann and Rainer Thiel<span style='color:#1F497D'>, </span>empirica Communication and Technology Research, Bonn, Germany<o:p></o:p></span></p><p class=MsoNormal style='margin-top:6.0pt'><i><span style='font-family:"Arial","sans-serif"'><o:p> </o:p></span></i></p><p class=MsoNormal style='margin-top:6.0pt'><i><span style='font-family:"Arial","sans-serif"'><o:p> </o:p></span></i></p><p class=MsoNormal style='margin-top:6.0pt'><i><span style='font-family:"Arial","sans-serif"'>How do you assess the impact of biocomputational models?<o:p></o:p></span></i></p><p class=MsoNormal style='margin-top:6.0pt'><span style='font-family:"Arial","sans-serif"'>In this webinar, you will learn about general principles to evaluate the prospective economic and clinical benefits of simulation methods. </span><span lang=DE style='font-family:"Arial","sans-serif"'>We will show how this approach enables you to:<o:p></o:p></span></p><p class=MsoListParagraph style='text-indent:-.25in;mso-list:l0 level1 lfo1'><![if !supportLists]><span lang=EN-GB style='font-family:Symbol'><span style='mso-list:Ignore'>·<span style='font:7.0pt "Times New Roman"'> </span></span></span><![endif]><span lang=EN-GB style='font-family:"Arial","sans-serif"'>Assess simulation research and translate technical capability into quantitative estimates of costs and benefits that go beyond model validation<o:p></o:p></span></p><p class=MsoListParagraph style='text-indent:-.25in;mso-list:l0 level1 lfo1'><![if !supportLists]><span lang=EN-GB style='font-family:Symbol'><span style='mso-list:Ignore'>·<span style='font:7.0pt "Times New Roman"'> </span></span></span><![endif]><span lang=EN-GB style='font-family:"Arial","sans-serif"'>Gain a better understanding about the impact such work can have on future health care service delivery and clinical practice<o:p></o:p></span></p><p class=MsoListParagraph style='text-indent:-.25in;mso-list:l0 level1 lfo1'><![if !supportLists]><span lang=EN-GB style='font-family:Symbol'><span style='mso-list:Ignore'>·<span style='font:7.0pt "Times New Roman"'> </span></span></span><![endif]><span lang=EN-GB style='font-family:"Arial","sans-serif"'>Demonstrate the added value of simulation research through clear measures of clinical benefits and the development of business cases <o:p></o:p></span></p><p class=MsoListParagraph style='text-indent:-.25in;mso-list:l0 level1 lfo1'><![if !supportLists]><span lang=EN-GB style='font-family:Symbol'><span style='mso-list:Ignore'>·<span style='font:7.0pt "Times New Roman"'> </span></span></span><![endif]><span lang=EN-GB style='font-family:"Arial","sans-serif"'>More effectively decide what aspects of the model should be included or excluded<o:p></o:p></span></p><p class=MsoNormal style='margin-top:6.0pt'><span style='font-family:"Arial","sans-serif"'>The webinar is targeted at biocomputational modellers and researchers as well as RTD funding agencies in the field of Virtual Physiological Human and Physiome. <b><o:p></o:p></b></span></p><p class=MsoNormal><b><span style='font-size:10.0pt;font-family:"Arial","sans-serif";color:#1F497D'><o:p> </o:p></span></b></p><p class=MsoNormal><b><span style='font-family:"Arial","sans-serif"'><o:p> </o:p></span></b></p><p class=MsoNormal><b><span style='font-family:"Arial","sans-serif"'>Tuesday, March 27, 2012<o:p></o:p></span></b></p><p class=MsoNormal><b><span style='font-family:"Arial","sans-serif"'>09:00 PDST/13:00 EST/18:00 CEST (UTC +02:00) <o:p></o:p></span></b></p><p class=MsoNormal><span style='font-family:"Arial","sans-serif"'>Duration: 60 minutes<o:p></o:p></span></p><p class=MsoNormal style='margin-top:6.0pt'><b><span style='font-family:"Arial","sans-serif"'>To register for the event, visit</span></b><span style='font-family:"Arial","sans-serif"'>: </span><span lang=DE><a href="https://stanford.webex.com/stanford/onstage/g.php?d=925320571&t=a"><span lang=EN-US style='font-family:"Arial","sans-serif"'>https://stanford.webex.com/stanford/onstage/g.php?d=925320571&t=a</span></a></span><span lang=DE style='font-family:"Arial","sans-serif"'> </span><span style='font-family:"Arial","sans-serif"'><o:p></o:p></span></p><p class=MsoNormal style='margin-top:6.0pt'><i><span style='font-family:"Arial","sans-serif"'><o:p> </o:p></span></i></p><p class=MsoNormal style='margin-top:6.0pt'><i><span style='font-family:"Arial","sans-serif"'><o:p> </o:p></span></i></p><p class=MsoNormal style='margin-top:6.0pt'><i><span style='font-family:"Arial","sans-serif"'>About this webinar<o:p></o:p></span></i></p><p class=MsoNormal style='margin-top:6.0pt'><span style='font-family:"Arial","sans-serif"'>The economic assessment method described reflects the latest research from the <i>NMS Physiome</i> project, a cooperation of two of the largest global research projects focusing on predictive, personalised and integrative musculoskeletal medicine: the Osteoporotic Virtual Physiological Human (VPHOP) project supported by the European Commission, and the Center for Physics-based Simulation of Biological Structures (SIMBIOS) at Stanford University, funded by the US National Institutes of Health.<o:p></o:p></span></p><p class=MsoNormal style='margin-top:6.0pt'><span style='font-family:"Arial","sans-serif"'>The Virtual Physiological Human (VPH) is a framework of methods and technologies that, once fully established, is expected to make possible the virtual investigation of the human body as a whole. Started in Europe in 2005, it has rapidly grown to become one of the research priorities of the Information and Communication Technologies Programme of the EU Seventh Framework Programme for Research and Technological Development, which runs from 2007 to 2013. In the US, VPH-type research is funded by all the federal agencies that participate in the Interagency Modeling and Analysis Group (IMAG), whose grantees are coordinated in the Multi-Scale Modeling (MSM) consortium.<o:p></o:p></span></p><p class=MsoNormal style='margin-top:6.0pt'><span style='font-size:10.0pt;font-family:"Arial","sans-serif";color:#1F497D'><o:p> </o:p></span></p><p class=MsoNormal><span style='font-family:"Arial","sans-serif"'>NMS Physiome is an international project co-funded by the European Commission Seventh Framework Programme for Research and Technological Development. The Webinar is hosted by SIMBIOS, Stanford University.<b><o:p></o:p></b></span></p><p class=MsoNormal><o:p> </o:p></p><p class=MsoNormal><o:p> </o:p></p><p class=MsoNormal><i><span style='font-size:10.0pt;color:#595959'>_______________________________________________<o:p></o:p></span></i></p><p class=MsoNormal><i><span style='font-size:10.0pt;color:#595959'><o:p> </o:p></span></i></p><p class=MsoNormal><i><span style='font-size:10.0pt;color:#595959'>Joy P. Ku, PhD<o:p></o:p></span></i></p><p class=MsoNormal><i><span style='font-size:10.0pt;color:#595959'>Director, Simbios<o:p></o:p></span></i></p><p class=MsoNormal><i><span style='font-size:10.0pt;color:#595959'><a href="http://simbios.stanford.edu"><span style='color:blue'>http://simbios.stanford.edu</span></a><o:p></o:p></span></i></p><p class=MsoNormal><i><span style='font-size:10.0pt;color:#595959'><o:p> </o:p></span></i></p><p class=MsoNormal><i><span style='font-size:10.0pt;color:#595959'>Director of Communications & Training,<o:p></o:p></span></i></p><p class=MsoNormal><i><span style='font-size:10.0pt;color:#595959'>National Center for Simulation in Rehabilitation Research<o:p></o:p></span></i></p><p class=MsoNormal><i><span style='font-size:10.0pt;color:#595959'><a href="http://opensim.stanford.edu"><span style='color:blue'>http://opensim.stanford.edu</span></a><o:p></o:p></span></i></p><p class=MsoNormal><i><span style='font-size:10.0pt;color:#595959'><o:p> </o:p></span></i></p><p class=MsoNormal><i><span style='font-size:10.0pt;color:#595959'>(W) 650.736.8434, (F) 650.723.7461<o:p></o:p></span></i></p><p class=MsoNormal><i><span style='font-size:10.0pt;color:#595959'>Email: <a href="mailto:joyku@stanford.edu"><span style='color:blue'>joyku@stanford.edu</span></a><o:p></o:p></span></i></p><p class=MsoNormal><o:p> </o:p></p></div></body></html>