Synopsis

The overall goal of this case study is to provide the utility of Open Knee(s) specimen-specific data - for evaluating mechanical function of the cruciate complex (anterior and posterior cruciate ligaments).

Use Case

The case is aimed at building a compartmental model of the cruciate complex using comprehensive specimen-specific data for one of the Open Knee(s) specimens. The goal is to develop kinematically driven model of the cruciate complex to evaluate the crutiate response under various loading conditions. This will also be helpful in developing a pipeline for model development using the geometric, joint and tissue mechanical information for a given knee joint. Effects of tissue geometry, insertion sites of the ligaments, material properties, bone geometry etc can then be evaluated on the cruciate complex mechanics (simulating effect of reconstruction surgeries).

Simulation Aims

• To build a finite element model of the cruciate complex supported by specimen-specific joint geometry, joint mechanical data and tissue properties.
• Develop list of specifications to build specimen-specific finite element model of a joint.
• Evaluate cruciate response under various geometric and mechanical conditions.

Model

• Geometry : Tibia, femur, anterior and posterior cruciate ligaments (ACL, PCL)
• Mesh
• Coordinate system registration
• Finite element model
• Ligament material properties
  • Constitutive model

Inputs

• Crutiate dominant kinematics

Outputs

• Time histories of kinetics of the cruciate complex.

Simulation Conditions

• Intact specimen-specific cruciate complex compartmental model
• Cruciate complex compartmental model with different insertion sites, material properties and tissue geometries.

Team Members

• Snehal Chokhandre - study planning, model development, execution of simulations and post-processing, lead authorship in publications
• Ahmet Erdemir - overall supervision

Progress

Source Code Repository

Data

Model Customization

Simulations

Post-Processing

Publications

References

• Jesal Parekh, "Using Finite Element Methods to Study Anterior Cruciate Ligament Injuries: Understanding the Role of ACL Modulus and Tibial Surface Geometry on ACL Loading." PhD Dissertation, The University of Michigan, 2013.

  http://deepblue.lib.umich.edu/handle/2027.42/97861

• Song Y1, Debski RE, Musahl V, Thomas M, Woo SL. "A three-dimensional finite element model of the human anterior cruciate ligament: a computational analysis with experimental validation."J Biomech. 2004 Mar;37(3):383-90.

  http://www.ncbi.nlm.nih.gov/pubmed/14757458