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[[TableOfContents]] <<TableOfContents>>
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= Synopsis = == Synopsis ==
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== Use Case == The overall goal of this case study is to provide the utility of Open Knee(s) - Generation 1 model for reproducing the outcome of a clinical test, the pivot shift, for evaluating mechanical function of the anterior cruciate ligament.
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== Simulation Aims == === Use Case ===
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== Model == The case is based on reproduction of a pivot shift loading scenario in a tibiofemoral joint model. The loading scenario was measured in a cadaver knee during pivot shift tests conducted by an orthopaedic surgeon. In follow-up robotics testing, this loading profile was adjusted for robotics testing of intact, ACL deficient, and ACL reconstructed knees. The use case aims for illustrating the capacity of the Open Knee(s) - Generation 1 model to reproduce the clinical differentiation of intact and ACL deficient knee in a virtual sense.
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== Inputs == === Simulation Aims ===
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== Outputs ==  * To understand the role of ACL for stabilization of the joint during pivot shift testing (primary)
 * To explore the correspondence of Open Knee(s) simulation against robotics prescribed pivot shift loading of various knees (secondary)
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== Simulation Conditions == === Model ===
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= Team Members = The model is based on Open Knee(s) - Generation 1 model, which was updated for FEBio version 2.1:
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= Progress =  . https://simtk.org/svn/openknee/_gen1/src/tf_joint_FEBio_v2.feb

=== Inputs ===

Prescribed time histories of movement and loading of the tibiofemoral joint (six degrees of freedom) representative of pivot shift data:

 * flexion
 * internal/external rotation torque
 * varus/valgus torque
 * anterior/posterior force
 * medial/lateral force
 * compression/distraction force

=== Outputs ===

 * Time histories of kinematics-kinetics of the tibiofemoral joint (six degrees of freedom) (primary)
  * flexion torque
  * internal/external rotation
  * varus/valgus
  * anterior/posterior translation
  * medial/lateral translation
  * compression/distraction
 * Time histories of stress-strain behavior (secondary)

=== Simulation Conditions ===

 * with intact ACL
 * without the ACL (very low stiffness for convenient modeling and simulation workflow)

== Team Members ==

 * Ahmet Erdemir - study planning, outline of publications
 * Snehal Chokhandre - execution of simulations and post-processing, lead authorship in publications
 * Craig Bennetts - assisting simulations, scripting for pre-/post-processing, support to document model in publications
 * Tara Bonner - assiting pivot shift trajectory generation, support documentation on pivot shift literature and implications of simulations for robotics testing
 * Robb Colbrunn - lead pivot shift trajectory generation, provide literature survey on pivot shift studies (clinical and cadaver testing), support to document implications of simulations for robotics testing
 * Paul Saluan - support to document clinical utility of pivot shift and implications of simulations for clinical practice

== Progress ==

=== Source Code Repository ===

https://simtk.org/svn/openknee/app/PivotShift/

=== Data ===

https://simtk.org/svn/openknee/app/PivotShift/dat/

=== Model Customization ===

https://simtk.org/svn/openknee/app/PivotShift/src/

=== Simulations ===

=== Post-Processing ===

https://simtk.org/svn/openknee/app/PivotShift/sol/

=== Publications ===

https://simtk.org/svn/openknee/app/PivotShift/doc/

== References ==

Synopsis

The overall goal of this case study is to provide the utility of Open Knee(s) - Generation 1 model for reproducing the outcome of a clinical test, the pivot shift, for evaluating mechanical function of the anterior cruciate ligament.

Use Case

The case is based on reproduction of a pivot shift loading scenario in a tibiofemoral joint model. The loading scenario was measured in a cadaver knee during pivot shift tests conducted by an orthopaedic surgeon. In follow-up robotics testing, this loading profile was adjusted for robotics testing of intact, ACL deficient, and ACL reconstructed knees. The use case aims for illustrating the capacity of the Open Knee(s) - Generation 1 model to reproduce the clinical differentiation of intact and ACL deficient knee in a virtual sense.

Simulation Aims

  • To understand the role of ACL for stabilization of the joint during pivot shift testing (primary)
  • To explore the correspondence of Open Knee(s) simulation against robotics prescribed pivot shift loading of various knees (secondary)

Model

The model is based on Open Knee(s) - Generation 1 model, which was updated for FEBio version 2.1:

Inputs

Prescribed time histories of movement and loading of the tibiofemoral joint (six degrees of freedom) representative of pivot shift data:

  • flexion
  • internal/external rotation torque
  • varus/valgus torque
  • anterior/posterior force
  • medial/lateral force
  • compression/distraction force

Outputs

  • Time histories of kinematics-kinetics of the tibiofemoral joint (six degrees of freedom) (primary)
    • flexion torque
    • internal/external rotation
    • varus/valgus
    • anterior/posterior translation
    • medial/lateral translation
    • compression/distraction
  • Time histories of stress-strain behavior (secondary)

Simulation Conditions

  • with intact ACL
  • without the ACL (very low stiffness for convenient modeling and simulation workflow)

Team Members

  • Ahmet Erdemir - study planning, outline of publications
  • Snehal Chokhandre - execution of simulations and post-processing, lead authorship in publications
  • Craig Bennetts - assisting simulations, scripting for pre-/post-processing, support to document model in publications
  • Tara Bonner - assiting pivot shift trajectory generation, support documentation on pivot shift literature and implications of simulations for robotics testing
  • Robb Colbrunn - lead pivot shift trajectory generation, provide literature survey on pivot shift studies (clinical and cadaver testing), support to document implications of simulations for robotics testing
  • Paul Saluan - support to document clinical utility of pivot shift and implications of simulations for clinical practice

Progress

Source Code Repository

https://simtk.org/svn/openknee/app/PivotShift/

Data

https://simtk.org/svn/openknee/app/PivotShift/dat/

Model Customization

https://simtk.org/svn/openknee/app/PivotShift/src/

Simulations

Post-Processing

https://simtk.org/svn/openknee/app/PivotShift/sol/

Publications

https://simtk.org/svn/openknee/app/PivotShift/doc/

References

Cases/PivotShift (last edited 2016-05-04 22:09:50 by localhost)