Recurring Meeting of Cleveland Clinic Core Team

Date: October 29, 2013

Time: 10:30 AM EST

Means: In person meeting

Attendees:

1. Ahmet Erdemir
2. Jason Halloran
3. Snehal Chokhandre
4. Robb Colbrunn
5. Tara Bonner

Agenda:

1. Discuss assigned tasks progress.
2. Decide meeting agenda and time for tissue testing equipment purchase.
3. Decide action items for next meeting.
4. Other

Immediate Action Items:

See notes for details.

• All

Notes:

1. Discuss assigned tasks progress.
   • Specimen specifications

     • ScienceCare can provide x-rays for assessment of osteoarthritis severity before order confirmation.

     • Snehal will update the specifications and request price information for 'pelvis to toe' specimens.
     • Some knee specimens used in the pivot shift test (Dr. Saluan) may be used in this project if they fit the need.
     • Suitable specimens from the surgical skills lab may also be used if needed.
   • Ahmet send the quote for Mach-1 tissue testing machine (Biomomentum, Inc) to Tara,Robb and Snehal and is awaiting response from NIH regarding equipment purchase.
   • Imaging specifications
     • For the meeting with Chris
     • CT may also be taken to obtain better bone geometry.
   • Documentation and publications
     • Tara and Robb will update the information regarding all the project related testing equipment (Mechanical testing infrastructure).
     • Scott will work on the Open knee generation 1 manuscript.
   • Imaging specifications
     • Craig updated the page with images and information for the current settings
     • Specimen transportation information will need to be updated.
     • To make sure that the marker placement is not disturbed and also to load the patella (to avoid crimped/ wavy ligaments during imaging), a fixture will be designed.
     • This fixture will have to be big enough to accommodate the knee specimen and the registration markers at the same time small enough to fit in the knee coil in the MRI.
2. Discuss tissue testing equipment purchase.
   • The overall expected cost for minimum required tissue testing (excluding indirect expenses) for 6 specimens is approximately $36k.
   • The goals is find the most cost effective solution.
   • Paying weekly or monthly for using the existing equipment may not be optimal since we will not be continuously testing all the specimens.
   • A more open access to the testing equipment is desirable in order to test more samples without the expenses exceeding the proposed budget.
   • New testing equipment may be purchased for the project which can also be used by the Bio-robotics core for other projects (fee for service).
   • The testing equipment from Biomometum Inc. is being considered which may provide a cost effective option to perform tissues testing for the project.
   • Robb,Tara and Snehal will talk to the Biomomentum engineers to make sure the testing equipment meets the project needs.