Recurring Meeting of Cleveland Clinic Core Team

Date: Nov 12, 2013

Time: 10:30 AM EST

Means: In person meeting

Attendees:

1. Ahmet Erdemir
2. Jason Halloran
3. Craig Bennetts
4. Snehal Chokhandre
5. Robb Colbrunn
6. Tara Bonner

Agenda:

1. Discuss tasks progress.(Finalize specimen specification to order specimens).
2. Discuss/finalize tissue testing equipment purchase.
3. Decide tasks for the next meeting.
4. Other

Immediate action items:

• Jason and Craig

  • Update relevant information for meetings with Univ of Utah and Stanford Univ. groups.

  Ahmet

  • Read joint testing specifications and make necessary edits.

  Jason and Snehal

  • Prepare information required for practice imaging session on Nov. 14th.

  Robb and Tara

  • Discuss cost estimates for using current tissue testing equipment.

Notes:

1. Discuss tasks progress.(Finalize specimen specification to order specimens).
   • Creation of tasks and Wiki pages was discussed.
   • Specimen specification
     • Snehal ordered two specimens (old, male and female, hip to toetips). Radiographs will be obtained for the specimens before finalizing the specimens.
     • More specimens will be procured as specifications evolve.
   • The issues related to mechanical testing (pressure sensor calibration, Optotrak issues etc.) need to be resolved before the testing can be done successfully.
   • Target test date for joint testing is set for last week of January 2014 or first week of February 2014.
   • At the end of first year (May 31st,2014) first specimen data collected and disseminated and modeling specifications need to be complete.
   • More specimens will be tested after first model built.
   • Imaging specifications
     • Jason, Craig and Snehal will test a few imaging protocols on Nov 14th.
   • Registration specifications and specimen preparation specifications.
     • Jason prepared a flowchart to describe the registration and initialization workflow.
     • Some changes were suggested to the flowchart. Change Opto (optotrack) to mocap (motion capture). Move T(Rob,Opto) to step 7. Change Anat to Anati.
     • Linking across the two specification pages needs to be clear.
     • Specimen preparation will be updated with all the information and registration math can be moved to later.
     • End dates will be updated.
   • Joint testing specifications
     • Tibiofemoral joint testing specifications are in usable form.
       • Equipment use modes were updated by Robb.
       • Initialization will be changes to coordinate system optimization to avoid confusion.
       • Repeatability testing stages were added.
       • Robb will update the naming convention.
       • Previous joint stretching data will be analysed to prepare secondary testing conditions. Using kinetics-kinematics for the joint and origin and insertion sites for the ligaments from MRI, stiffness and slack lengths may be estimated for the ligaments. (Prescribe ligament stiffness and obtain slack lengths).
     • Patellofemoral joint testing information is mostly done. Ahmet will go over the information and make necessary updates.
     • Jason contacted Tekscan to get sensor and software pricing and equivalencing (known equal load on each sensol) hardware.
     • Test workflow for cloud computing
       • Craig is working on all the required scripts.
       • All information will be updated before the meeting with Stanford Univ. group.
     • Tissue testing specifications
       • Snehal will test tendon specimens in the next couple of weeks.
       • Anterolateral ligament may be added as a secondary tissue.
     • Task was created to add imaging infrastructure.
     • FEBio feature task
       • Task will be assigned to the Univ. of Utah group to create Wiki page for progress updates.
     • Robb created tasks for tracking verification of spatial registrations.

2. Discuss/ finalize tissues testing equipment purchase.

• Cost estimates are required for the Biomomentum machine with video sync and force control upgrades.
• Cost comparison was done for buying the equipment vs using existing machine.
• The total cost for buying the machine that meets all our requirements is $46,000 (machine will be available for unlimited use and other projects).
• Direct cost for testing minimum number of samples is $32,400 (indirect cost= $18,954).
• Robb and Tara will discuss the costs and inform the team their decision.
• Delivery and training time for the new machine will be 2-3 months.

3. Discuss tasks for next meeting.

• See immediate action items above.