Recurring Meeting of Cleveland Clinic Core Team

Date: Nov 19, 2013

Time: 10:30 AM EST

Means: In person meeting

Attendees:

1. Ahmet Erdemir
2. Jason Halloran
3. Craig Bennetts
4. Snehal Chokhandre
5. Robb Colbrunn
6. Tara Bonner

Agenda

1. Discuss tasks progress.
2. Discuss specimen transportation device design.
3. Finalize tissue testing equipment purchase.
4. Decide tasks for the next meeting.
5. Other

Immediate action items

• Jason

  • Update FEBio feature specifications for upcoming conference call with University of Utah.

  Craig

  • Update cloud computing specifications for upcoming conference call with Stanford University.
  • Get foam samples for specimen transportation device.

  Robb and Snehal

  • Prepare list of desired features for tissue testing device (including primary and secondary features based on exact tissue testing needs, and pricing).

  Jason and Snehal

  • Review imaging data and update relevant Wiki pages.

  Snehal

  • Get MRI machine specifications and knee coil dimensions.

Notes

1. Discuss task progress

• Immediate action items were discussed. Details are provided in the following notes.
• Imaging specifications
  • Jason and Snehal conducted a test session at University Hospitals to try some imaging sequences and check the brass marker fixtures for observed imaging artefacts.
  • One of the OAI protocols (DESS) were tried along with a T2 proton density protocol
  • Implementing the OAI protocol was challenging as the clinical scanners have restrictions on controls.
  • One of the UH engineers will try to program the specific protocol offline which can be tried in the next test session.
  • The protocol tested was the closest that could be programmed online.
  • Every brass piece from the phantom was noticed to be causing some artefact. Delrin or medical grade brass/ stainless steel that can be fixed / screwed into bone might be considered.
  • Jason will contact Dr. Winalski for advice on suitable materials.
  • Delrin/ phenolic fixtures and metal screws may be used in the worst case.
  • Alignment pins have to be metallic.
  • If medical grade materials are used they have to be MRI grade too.

1. Finalize tissue testing equipment purchase.
   • One of the proposed alternatives to tissue testing was to gain access to the existing system at a fixed price for 4 years.

   • The BioRobotics Core decided that it difficult to compete at the requested price and therefore the team has decided to purchase the testing equipment for the project.

   • The maximum budget for the equipment is $45,000 and needs to include all the specifications.
     • 3 axis controller (not 3 axis motors), if 6 axis load cell can be bought now it will useful
     • Video system sync is important than multi axial load cell currently.
     • Minimum machine requirements (quote will be requested based on these): 3 axis controller , 0.5 micrometer resolution (0.1 micrometer resolution is another $4k(for motor)), single axis load cell, camera, fixtures, manual x-y control, bath with heater, additional: multi axis load cell, 0.1 micrometer resolution. (base machine: $34k,camera: $3k). Higher res capability will be preferred over multiaxis load cell for upgrade as capability to apply strains with better accuracy is desirable.
     • Robb and Snehal will prepare an itemized list with estimated cost for the minimum desirable machine and the ideal machine.
     • The Bose Electroforce test instrument will not work for the project as the stroke is only 2.5 mm.
     • The MTS controller box works with any MTS testing machine. If a frame that meets our testing requirements can be bought, we can save a significant amount using the existing controller box.
     • Based on the quotes and specifications of all testing machines, one machine will be decided upon in the next meeting.

4. Decide tasks for the next meeting