Recurring Meeting of Cleveland Clinic Core Team

Date: February 4, 2014

Time: 10:30 AM EST

Means: In person meeting

Attendees:

1. Ahmet Erdemir
2. Jason Halloran
3. Craig Bennetts
4. Robb Colbrunn
5. Tara Bonner
6. Cara Sullivan

Agenda:

1. Discuss immediate action items from the last meeting.
2. Update from imaging trial session and finalization of imaging specifications.
3. Update on pressure measurement system evaluation and related purchase list.
4. Update on manufacturing of remaining accessories for joint and tissue testing.
5. Discuss progress on specimen preparation specifications.
6. Discuss progress of all other tasks.
7. Decide immediate action items for the next meeting.
8. Other.

Immediate Action Items:

• Ahmet
  • Add Dylan and Cara as project team members.
• Jason
  • Complete description of specimen transportation to imaging facility.
• Craig
  • Contact Chris or Shannon (from the imaging facility) to complete the table of imaging parameters.
  • Acquire appropriate image sets from last imaging trial session for review.
  • Explore co-localization (coordinate system alignment) of image sets.
• Robb
  • Start manufacturing four base plugs for femur, tibia, and patella.
  • Start manufacturing the patella female attachment construct.
• Tara
  • Follow up the purchasing of the software upgrade and 5 pressure sensors from Tekscan, Inc.
  • Continue editing the specimen preparation page.

• Craig & Tara

  • Test the spatial requirement of patella marker assembly within the transportation device.
• Robb and Jason
  • Evaluate equilibration and calibration protocols for pressure sensors.
• Robb and Ahmet
  • Meet for tank design and camera calibration protocols for tissue testing.
• All
  • Come up with design ideas for patella marker set.

Notes:

1. Discuss immediate action items from the last meeting.
   • Jason briefly discussed his action items. Details are provided in relevant topics described below.
   • Tara provided additional details and links to the specimen preparation page.
   • Robb reported that Dylan will order small heaters for the temperature controlled saline bath that will be used during tissue testing.
   • Notes from the last meeting were discussed.
     • There has not been any contact from Biomomentum, Inc. about the tissue testing device. The team assumes everything is on schedule.
     • Dylan is writing up a report about his troubleshooting of the Optotrak two-camera accuracy.
     • The surgeon(s) need to be contacted soon for scheduling experimentation in late February and/or early March, to help the first of Open Knee(s) testing.
     • An aside, Ahmet had an interview with Crain's Business Cleveland. An Open Knee(s) related article, driven by its open source nature, may be published in an upcoming issue.
2. Update from imaging trial session and finalization of imaging specifications.
   • Jason and Craig discussed the transportation device. A workflow was made to desrcribe the process and was added to the wiki. Jason will update the text to reflect the discussion and the proposed workflow. Essentially, details need to be added related to maintaining cleanliness, the required tools and the duffel bag location, etc.
   • Craig summarized the test image session and updated the imaging specifications page to include an "OAI style" summary of the acquisition settings. All fields in the table need to be completed. The UH imaging contacts will be asked about image settings and how to interpret the DICOM header data (to populate the unknown image parameters). We still need to establish the consistency of coordinate frames for each set of acquisition parameters (I believe this is called "co-localization"). Craig proposes that we decide on the echo time parameter for the MESE settings, especially if it is an acquisition type that we're going to use.
     • Images from last week's test session were viewed. The phantoms were discussed first and it appears none of the candidate materials caused significant distortion/noise in the image set. The knee images appear to be the wrong data set. Craig and/or Jason will talk with Shannon at UH to verify and acquire the correct image set. The group (Ahmet, Jason, and/or Craig) will meet later in the week to decide on the final image settings.
     • Related, a design for the plugs (the male and female hardware to mount the Optotrak and phantoms) needs to be decided on and manufactured. For the tibia and femur, at least two base plugs need to be manufactured. For the patella, a base plug plus the attachment device (the female component) with the brass alignment pins will be manufactured according to the previous design. For completeness, Tara and Craig and will test the patella phantom to qualify its use during imaging. There is concern that it will not fit in the transport device for imaging, especially for larger knees. For next week, an approach will be proposed, which may include a re-design of the patella imaging registration markers.
3. Update on pressure measurement system evaluation and related purchase list.
   • The group discussed our pressure measurement needs and the available hardware/software from Tekscan. At a minimum, we will order the software upgrade and 5 new 5051 sensors. Robb and Jason will outline and potentially execute (using the old software) an approach for equilibration and calibration. The foot testing bladder system (capable of up to 87 psi) will be used for equilibration and plastic spheres will be used for calibration. Tara will place the order for the software and sensors. Robb and Tara will decide whether the SDK should also be purchased for future testing. Adoption of the SDK software will require an investment, i.e. the design and integration into the current workflow, which precludes its use for the first round of testing. "Manual" acquisition of pressures will be adopted during the first testing of the first Open Knees specimen. Future testing could integrate this capability if it is deemed worthwhile.
4. Update on manufacturing of remaining accessories for joint and tissue testing.
   • Robb and Ahmet need to talk about the camera calibration and a redesign of the environment tank for the tissue testing. They will setup a meeting to discuss.
5. Discuss progress on specimen preparation specifications.
   • Tara discussed the specimen preparation. Tara will start answering questions on this page. The group needs to edit/view this page for competeness
     • Related, specifications for registration should be edited, at least the input-output requirements so that the desired data is acquired.
6. Discuss progress of all other tasks.
   • No other tasks were discussed.
7. Decide immediate action items for the next meeting.
   • Ahmet summarized the Immediate Action Items (see above). The team agreed that the tasks were appropriate.
8. Other.
   • None.