Recurring Meeting of Cleveland Clinic Core Team

Date: February 11, 2014

Time: 10:30 AM EST

Means: In person meeting

Attendees:

1. Ahmet Erdemir
2. Jason Halloran
3. Craig Bennetts
4. Snehal Chokhandre
5. Robb Colbrunn
6. Tara Bonner
7. Cara Sullivan

Agenda:

1. Discuss immediate action items from the last meeting.
2. Update on imaging.
3. Update on pressure measurement.
4. Update on manufacturing of testing accessories.
5. Update on specimen preparation specifications.
6. Discuss progress of all other tasks.
7. Decide immediate action items for the next meeting.
8. Other.

Immediate Action Items:

• Robb and Jason
  • Prototype an equilibration and calibration procedure with pressure measurement system.
• Robb and Craig
  • Modify patella marker assembly design and get it manufactured.
• Ahmet, Craig and Snehal
  • Check with Chris Flask to setup and complete an full mock-up imaging session.
  • Prepare mock-up specimen for imaging.
• Robb and Tara
  • Complete robotics testing related upgrade tasks.
• Snehal
  • Respond requests in the infrastructure page of tissue testing experimentation.
  • Respond requests in tissue sample preparation pages.
• Cara
  • Meet everyone to understand their data management needs.

Notes:

1. Discuss immediate action items from the last meeting.
   • Ahmet added Cara and Dylan to the project team.
   • Jason summarized the specimen transportation page
   • Craig sent a detailed email to the imaging at UH about our current issues. Ahmet also discussed with Chris Flask about our needs. We'll need another trial session. Ahmet summarized the approach on the imaging specifications page.
   • Robb ordered base plugs for the tibia and femur. Craig and Tara verified that the existing patella marker is too large. The patella marker set will be redesigned by Craig and will be implemented as a CAD drawing by a member of Medical Device Solutions. It is anticipated to be a “wrapping” design that somewhat conforms to the patella and will also wrap inside the transportation tube. The immediate action for the patella marker is to modify and manufacture the design per our discussion. Essentially, this includes adding some chamfers and probing divots to the existing design.
   • Tara had the Tekscan order placed by the BME administration.
   • Tara updated the specimen preparation page. This will be discussed in the specific action item.
   • The team assumes that the order with Biomomentum, Inc. is on schedule.
2. Update on imaging.
   • Ahmet summarized his discussions with Chris Flask under the “OAI style” imaging table. Ahmet confirmed that the OAI settings were a starting point. Chris provided his interpretation of the image settings. There was a miscommunication about image alignment. As long as the specimen does not move, all image sets should be aligned in the same coordinate system. We do not require “co-localization”, which we interpret as voxel-by-voxel alignment between image sets.
   • The progression of sequences, from 1 to 3, were summarized. Sequence 3, the MESE settings, still need to be tested. Ahmet proposes that the next imaging test session is essentially a mock-up of the work flow. Ahmet and Craig will schedule the next test session.
   • The team discussed alternative registration markers for the tibia and patella. As of now, the default is the traditional approach but are considering alternative designs that utilize the existing plugs (for the Optotrak).
3. Update on pressure measurement.
   • Robb and Jason will attempt an equilibration and calibration approach for pressure measurements.
4. Update on manufacturing of testing accessories.
   • Ahmet believes that most, if not all, accessories are manufactured. This primarily refers to the hardware.
   • The saline bath and associated heater were discussed. Images of the specimen during testing, due to the cylindrical bath, will be distorted in the current setup. The tank will likely need to be modified to provide a clear/undistorted picture of the specimens during testing.
   • The robotics testing software needs to be updated to reflect the hardware changes. Dylan received the new probe for digitization of landmarks and calibration is ongoing. Robb summarized an issue with a new computer and corresponding control of the robot. The older computer can always be used as a default but a new setup is being troubleshot.
5. Update on specimen preparation specifications.
   • Tara added a pdf of the specimen labeling approach for soft-tissue testing. Numbering was proposed, which should be tied to metadata that describes the test.
   • A long discussion was centered around metadata and its association with the specimen numbering/naming. The approach will be decided as we progress as a convention for populating metadata and the naming should be. The specifications wiki page related to data management should be used for discussions and to set the specifics.
6. Discuss progress of all other tasks.
   • Snehal will update the experimentation infrastructure page to summarize the tissue testing facilities, grips, etc.
7. Decide immediate action items for the next meeting.
   • Ahmet summarized the Immediate Action Items (see above). The team agreed that the tasks were appropriate.
8. Other.
   • None noted.