Recurring Meeting of the Advisory Board

Date(s): November 20-21, 2014

Due to scheduling conflicts, the group meeting with the Advisory Board members were scheduled on an individual basis with each member. Please refer to Meeting Minutes for more details.

TableOfContents

Progress Report

Project Specific Aims

• To provide an open, freely available, and collaborative development, testing, simulation and dissemination platform for in silico exploration of the biomechanics of healthy and diseased knees.
• To develop in silico biomechanical models of healthy and diseased knee joints of different genders and ages, supported by specimen-specific joint and tissue level experimental mechanics.

Project Infrastructure

• https://simtk.org/home/openknee (project website)

• http://wiki.simtk.org/openknee (project wiki)

Project Contact

• Ahmet Erdemir, PhD, erdemira@ccf.org, https://simtk.org/users/aerdemir

Advisory Board

• Clinical. Jack Andrish, MD; Carl Winalski, MD; Morgan Jones, MD, MPH; Paul Saluan, MD (Cleveland Clinic)

• Engineering. Yasin Dhaher, PhD (Northwestern University); Trent Guess, PhD (University of Missouri), Rami Korhonen, PhD (University of Eastern Finland)

Progress Period

• May 19, 2014 - November 20, 2014

Development Team during Progress Period

• Cleveland Clinic Core Team. Craig Bennetts, Tara Bonner, Snehal Chokhandre, Robb Colbrunn, Ahmet Erdemir, Jason Halloran

• Stanford University. Scott Delp, Joy Ku, Henry Kwong

• University of Utah. Ben Ellis, Jeff Weiss, Steve Maas

• Community. Shannon Donnola, Chris Flask, Katie Stemmer

See https://simtk.org/project/xml/team.xml?group_id=485 for full details on the project team.

Goals of Progress Period

• Enhance prototype of web based computation infrastructure (Stanford University)
• Implement additional features in simulation software (University of Utah)
• Complete experimentation for Specimen 001 (Cleveland Clinic)
• Complete experimentation for Specimen 002 (Cleveland Clinic)
• Launch model for Specimen 001 (Cleveland Clinic)

• Complete development and review of modeling specifications (Cleveland Clinic & Community)

• Complete development and review of simulations specifications (Cleveland Clinic & Community)

• Start plans for 2015 summer internship program as part of community projects (reviews, internships, and collaborations) (Cleveland Clinic & Community)

• Publish previous work on Open Knee - Generation 1 (Cleveland Clinic)

Please also refer to previous meeting minutes of the Advisory Board at ["RecurringMeetings/2014-05-19"]. It should be noted that the timeline of activities has deviated from the original proposal, i.e., see the ["Roadmap"] and the proposed timeline of the proposal in attachment:GrantInformation/proposal.pdf.

Activities of Progress Period

• Cloud computing prototype

  • Cleveland Clinic and Stanford University teams continued to have monthly conference calls to to discuss web based computation interface. Please refer to meeting minutes in Cleveland Clinic - Stanford University section of RecurringMeetings.

  • Detailed specifications on a prototype for web-based computing infrastructure can be found at the wiki page [http://wiki.simtk.org/openknee/Specifications/CloudComputingPrototype?action=recall&rev=19 Revision as of November 19, 2014] or [:Specifications/CloudComputingPrototype: current version].

Clinic team, see Revision as of May 18, 2014 or current version.

• SimTk.org site is currently under the process of migration to upgrade the infrastructure.

• Web-based interface for submissions of simulations and for results retrieval were implemented and tested on a staging server. The team is waiting for SimTk.org upgrade to launch the cloud computing interface.

• Upcoming steps include development of a model administration interface, implementation of quota management features, and public release of the cloud computing infrastructure.

• Simulation software features
  • TBD
• Experimentation
  • TBD

• Modeling & simulation

  • TBD
• Dissemination
  • TBD
• Community projects
  • TBD
• Publications
  • TBD
• Other
  • TBD

Details of activities can be found in past meeting minutes of various teams at ["RecurringMeetings"].

Plans for Next Progress Period (November 20, 2014 - May 2014)

• Launch and enhance web based computation infrastructure (Stanford University)
• Implement additional features in simulation software (University of Utah)
• Disseminate joint imaging and joint mechanics data for oks001, oks002, oks004 (Cleveland Clinic)
• Complete joint imaging and joint mechanics experimentation on oks003, oks005, oks006, oks007 (Cleveland Clinic)
• Complete tissue mechanics testing of oks001, oks002, oks004 (Cleveland Clinic)

• Continue development and review of modeling and simulation specifications (Cleveland Clinic & Community)

• Start developing models for oks001, oks002, oks004 (Cleveland Clinic)
• Upgrade and disseminate Open Knee(s) - Generation 1 (Cleveland Clinic)

• Implement 2015 summer internship program as part of community projects (Cleveland Clinic & Community)

• Publish previous work on Open Knee - Generation 1 (Cleveland Clinic)

It should be noted that the timeline of activities has deviated from the original proposal, i.e., see the ["Roadmap"] and the proposed timeline of the proposal in attachment:GrantInformation/proposal.pdf.

Meeting Minutes

Date, Time, Means:

• November 20, 2014, 9:00 AM EST, in person meeting (JA)
• November 20, 2014, 12:30 PM EST, in person meeting (PS)
• November 20, 2014, 2:00 PM EST, conference call (TG)
• November 21, 2014, 9:00 AM EST, conference call (RK)
• November 21, 2014, 12:00 PM EST, conference call (YD)

Attendees:

1. Ahmet Erdemir (Cleveland Clinic)
2. TBD

Agenda:

1. Progress update, see progress report at:

   • http://wiki.simtk.org/openknee/RecurringMeetings/2014-11-20

2. Recap of previous meeting minutes, see meeting minutes at:

   • http://wiki.simtk.org/openknee/RecurringMeetings/2014-05-19

3. Action items for following meeting.
4. Other.

Immediate Action Items:

See notes for details.

• All Advisory Board Members

  • TBD

• Ahmet Erdemir

  • TBD

Notes:

1. Due to scheduling conflicts, a series of meetings were conducted to inform the Advisory Board about Open Knee(s) activities and get feedback.
2. Progress update.
   • TBD
3. Recap of previous meeting minutes.
4. Action items for following meeting.
   • TBD
5. Other.
   • TBD