Recurring Meeting of Cleveland Clinic Core Team

Date: May 5, 2015

Time: 10:30 AM EST

Means: In person meeting

Attendees:

1. Ahmet Erdemir
2. Craig Bennetts
3. Snehal Chokhandre
4. Robb Colbrunn
5. Tara Bonner

Agenda:

1. Discuss immediate action items from the last meeting.
2. Continue discussion on large-scale analysis of simulation parameters for FE model convergence.
3. Discuss Mach-1 tissue testing system updates and test plans.
4. Decide immediate action items for the next meeting.
5. Other.

Immediate Action Items:

• Ahmet
  • Complete the progress report for Advisory Board meeting.
• Craig
  • Conduct convergence analysis study with different simulation parameters for passive flexion up to 90 degrees.

• Robb & Tara

  • Provide brief documentation on tdms file contents (groups & channels).

Ongoing Action Items:

• Ahmet
  • Dissemination of joint mechanics testing data.
  • Detail image segmentation specifications.
• Craig
  • Anatomical imaging manuscript.
  • Large-scale analysis of simulation parameters for convergence.
• Snehal
  • Pivot shift manuscript.

  • Cruciate ligament modeling & simulation.

  • Evaluate alternative tissue testing strategy.
• Robb
  • Patellofemoral joint experimentation manuscript.
  • Conversion of patellofemoral joint contact pressure data to ASCII format.
• Tara
  • Tibiofemoral joint experimentation manuscript.

Notes:

1. Discuss immediate action items from the last meeting.

   • Ahmet told the group that repository browsing is possible. Yet the links to allow online browsing of the repository are not advertised at the SimTk.org site. Per Joy, activation of this feature can be prioritized if there are requests from users.

   • Ahmet started the progress report for the Advisory Board meeting, which is scheduled to begin this week.

   • Snehal already found and started to read the manuscripts by Yasin Dhaher on ACL reconstruction. These manuscripts will provide background information necessary for cruciate ligament modeling & simulation.

   • Craig submitted the requests to update computers for the summer students. The team should receive at least one of these before May 18, 2015, when the first student will show up.
   • Robb and Tara will complete the documentation on tdms file contents today and provide the information in the relevant infrastructure page of the wiki.
   • Ongoing work on the dissemination of joint mechanics data awaits for the documentation on tdms files.
   • Craig and Ahmet will discuss the outline of the upcoming anatomical imaging presentation. This will aide the development of the manuscript.

   • Patellofemoral joint contact pressure data are being converted to ASCII format by a high school student working for the BioRobotics Core facility.

   • The remainder of ongoing activities did not have any considerable progress.
2. Continue discussion on large-scale analysis of simulation parameters for FE model convergence.
   • Craig conducted analysis to explore the role of loading on convergence characteristics. Simulations had a difficulty to converge particularly during the application of joint moments. Large flexion angles also caused problems. Ahmet advised to try to solve passive flexion up to 90 degrees (rather than 45 degrees) using different simulation parameters to see if adjusting these help obtain a solution. Craig will follow up.
3. Discuss Mach-1 tissue testing system updates and test plans.
   • Snehal noted that for alternative testing (load-unload using ramp), a wait time of 30 minutes may not be enough. Ahmet asked if Snehal compared the absolute displacement-force data or one referenced to finding initial contact. This may cause discrepancies, these tests may need to be conducted again with the same exact displacement profile (starting slightly above the compression specimen) without a find contact step. In following, displacement-force curves can be compared to see if they lay on top of each other.
   • Snehal also tried conducted ramp and hold (on foam samples) with improved acceleration settings for the testing system. The system exhibited difficulties to apply velocities representing 100%/s strain rate at to reach a desired displacement amplitude. Testing at 20%/s strain rate appeared to be fine, including appropriate matching of the timings of peak force and displacement. She will explore the possibility to apply 50%/s strain rate.
   • The group discussed displacement and velocity requirements of tests. Based on a minimum compressing sample thickness of 1.5 mm and a strain increment of 2.5%, the testing system should be evaluated to move 0.0375 mm at a velocity of 1.5 mm/s. Based on a maximum tensile sample length of 15 mm and a strain increment of 3%, the testing system should be evaluated to move 0.45 mm at a velocity of 15 mm/s.
4. Decide immediate action items for the next meeting.
   • See Immediate Action Items above.
5. Other.
   • Ahmet reminded the team that Yasin Dhaher from the Advisory Board will be visiting Cleveland Clinic on upcoming Friday. All were encouraged to join to the meeting with him and Morgan Jones and Jack Andrish (other members of the Advisory Board) scheduled for 11 AM that day.