Recurring Meeting of the Advisory Board

Date(s): May 7-21, 2015

Due to scheduling conflicts, the group meeting with the Advisory Board members were scheduled on an individual basis with each member. Please refer to Meeting Minutes for more details.

TableOfContents

Progress Report

Project Specific Aims

• To provide an open, freely available, and collaborative development, testing, simulation and dissemination platform for in silico exploration of the biomechanics of healthy and diseased knees.
• To develop in silico biomechanical models of healthy and diseased knee joints of different genders and ages, supported by specimen-specific joint and tissue level experimental mechanics.

Project Infrastructure

• https://simtk.org/home/openknee (project website)

• http://wiki.simtk.org/openknee (project wiki)

Project Contact

• Ahmet Erdemir, PhD, erdemira@ccf.org, https://simtk.org/users/aerdemir

Advisory Board

• Clinical. Jack Andrish, MD; Carl Winalski, MD; Morgan Jones, MD, MPH; Paul Saluan, MD (Cleveland Clinic)

• Engineering. Yasin Dhaher, PhD (Northwestern University); Trent Guess, PhD (University of Missouri), Rami Korhonen, PhD (University of Eastern Finland)

Progress Period

• November 20, 2014 - May 7, 2015

Development Team during Progress Period

• Cleveland Clinic Core Team. Craig Bennetts, Tara Bonner, Snehal Chokhandre, Robb Colbrunn, Ahmet Erdemir

• Stanford University. Scott Delp, Joy Ku, Henry Kwong

• University of Utah. Ben Ellis, Jeff Weiss, Steve Maas

• Community. Shannon Donnola, Chris Flask

See https://simtk.org/project/xml/team.xml?group_id=485 for full details on the project team.

Goals of Progress Period

• Launch and enhance web based computation infrastructure (Stanford University)
• Implement additional features in simulation software (University of Utah)
• Disseminate joint imaging and joint mechanics data for oks001, oks002, oks004 (Cleveland Clinic)
• Complete joint imaging and joint mechanics experimentation on oks003, oks005, oks006, oks007 (Cleveland Clinic)
• Complete tissue mechanics testing of oks001, oks002, oks004 (Cleveland Clinic)

• Continue development and review of modeling & simulation specifications (Cleveland Clinic & Community)

• Start developing models for oks001, oks002, oks004 (Cleveland Clinic)
• Upgrade and disseminate Open Knee(s) - Generation 1 (Cleveland Clinic)

• Implement 2015 summer internship program as part of community projects (Cleveland Clinic & Community)

• Publish previous work on Open Knee - Generation 1 (Cleveland Clinic)

Please also refer to previous meeting minutes of the Advisory Board at ["RecurringMeetings/2014-11-20"]. It should be noted that the timeline of activities has deviated from the original proposal, i.e., see the ["Roadmap"] and the proposed timeline of the proposal in attachment:GrantInformation/proposal.pdf.

Activities of Progress Period

• Cloud computing prototype

  • Cleveland Clinic and Stanford University teams continued to have bi-monthly conference calls to discuss web based computation interface. Please refer to meeting minutes in Cleveland Clinic - Stanford University section of ["RecurringMeetings"].

  • Detailed specifications on a prototype for web-based computing infrastructure can be found at the wiki page [http://wiki.simtk.org/openknee/Specifications/CloudComputingPrototype?action=recall&rev=19 Revision as of May 6, 2015] or [:Specifications/CloudComputingPrototype: current version].

  • The team at the Stanford University mainly focused on the upgrade of the SimTk.org infrastructure. The launch of the updated site has been delayed.

  • In the previous progress report, it was noted that web-based interfaces for submissions of simulations and for results retrieval had been implemented and tested on a staging server. The team has been waiting for SimTk.org upgrade for the public release of the cloud computing interface. In following, usability testing of the infrastructure can be performed.

  • Following usability testing (anticipated to happen after the launch of updated SimTk.org site], the development of a model administration interface and the implementation of quota management features will be conducted.

  • The Cleveland Clinic team applied for a hardware grant from a commercial company with the intention to provide a dedicated high performance computing infrastructure for Open Knee(s). The application was not successful.
• Simulation software features
• Experimentation

• Modeling & simulation
• Dissemination
• Community projects
• Publications

Details of activities can be found in past meeting minutes of various teams at ["RecurringMeetings"].

Plans for Next Progress Period (May 7, 2015 - November 2014)

It should be noted that the timeline of activities has deviated from the original proposal, i.e., see the ["Roadmap"] and the proposed timeline of the proposal in attachment:GrantInformation/proposal.pdf.

Meeting Minutes

Date, Time, Means:

• TBD

Attendees:

1. TBD

Agenda:

1. Progress update, see progress report at:

   • http://wiki.simtk.org/openknee/RecurringMeetings/2015-05-07

2. Recap of previous meeting minutes, see meeting minutes at:

   • http://wiki.simtk.org/openknee/RecurringMeetings/2014-11-20

3. Action items for following meeting.
4. Other.

Immediate Action Items:

See notes for details.

• All Advisory Board Members

  • TBD

• Ahmet Erdemir

  • TBD

Notes:

1. Due to scheduling conflicts, a series of meetings were conducted to inform the Advisory Board about Open Knee(s) activities and get feedback.
2. Progress update.
   • TBD
3. Recap of previous meeting minutes.
   • TBD
4. Action items for following meeting.
   • See Immediate Action Items above.
5. Other.
   • TBD