Recurring Meeting of Cleveland Clinic Core Team

Date: January 19, 2016

Time: 10:30 AM EST

Means: In person meeting

Attendees:

1. Ahmet Erdemir
2. Craig Bennetts
3. Robb Colbrunn
4. Tara Bonner

Agenda:

1. Discuss immediate action items from the last meeting.
2. Discuss first drafts of data manuscripts.
3. Decide immediate action items for the next meeting.
4. Other.

Immediate Action Items:

• Ahmet
  • Work on segmentation of MCL of oks001.
• Craig
  • Document manual segmentation in the relevant specifications page.
  • Document output of segmented volumes as surfaces in the segmentations specifications page.
  • Work on recommendations discussed in the meeting for the imaging manuscript.
• Snehal
  • Change protocols for tissue testing to separate zero load displacement estimation using "find contact".
  • Expand documentation of the results of tissue testing protocol evaluations.
  • Update tissue testing analysis script to identify zero force displacement (next two weeks).
  • Write a Python script for manual identification of tissue thickness from tissue images (next two weeks).
• Jason
  • Provide the background for the patellofemoral joint testing manuscript.
• Robb
  • Complete the first draft of the patellofemoral joint testing manuscript.
  • Read the manuscript on magnetic resonance imaging paper.
• Tara
  • Review sections of the patellofemoral joint testing manuscript.
  • Complete tibiofemoral joint testing manuscript.

Ongoing Action Items:

DEADLINE FOR SECOND DRAFT DATA PAPERS IS APRIL 1, 2016

• Ahmet
  • Prepare flowcharts to describe data flow for pre-processing of joint kinematics/kinetics data.
• Craig
  • Anatomical imaging manuscript.
  • Large-scale analysis of simulation parameters for convergence.
• Snehal
  • Add citations and summaries to tissue data papers to the wiki for potential use to model tissue properties.
  • Pivot shift manuscript.

  • Cruciate ligament modeling & simulation.

• Robb
  • Patellofemoral joint experimentation manuscript.
• Tara
  • Tibiofemoral joint experimentation manuscript.

Notes:

1. Discuss immediate action items from the last meeting.
   • Ahmet worked with Slicer to familiarize loading image sets and segmentations and to start segmenting the medial collateral ligament (MCL). Based on his experience, he recommended Craig to briefly summarize tools available for manual segmentation in the specifications page. In addition, he mentioned surface (STL) output options that need to be documented in the specifications. Ahmet also showed some FreeCAD features that may be useful to work with STL surfaces, e.g. manual trimming of triangular surface meshes, sketching on planes that are arbitrarily oriented, etc.
   • Craig added documentation for registration marker segmentation. He still needs to evaluate registration marker segmentations done by summer students. Craig and Ahmet previously discussed approaches for segmentation and modeling workflows and how best to use available resources and time. Ahmet noted that a team member (or a group) will likely focus on getting the whole modeling workflow completed on one knee, while the other members can focus on the analysis of other knees based on matured specifications, e.g. segmentation.
   • Snehal was out of town for most of the week. The group will catch up with her in the following week.
   • Jason has not provided background for patellofemoral joint testing manuscript. The group will follow up with him next week.
   • Robb did some work on the patellofemoral joint manuscript and he is part way through reviewing the manuscript on imaging.
   • Tara needs to look at the patellofemoral joint testing manuscript to help Robb. She is planning to add some RMS error calculations to the tibiofemoral joint testing manuscript. She will work with Snehal to find literature on tibiofemoral joint laxity data to incorporate into the manuscript.
2. Discuss first drafts of data manuscripts.
   • TBD
3. Decide immediate action items for the next meeting.
   • See Immediate Action Items above.
4. Other.
   • Ahmet noted that our activities are at an inflection point in between experimentation and modeling. He mentioned that the Open Knee(s) funding will end by the end of May 2017. He discussed with the group potential proposals he will be submitting. Ideally, a renewal application need to be submitted by June 2016, i.e. if funded, this will ensure continuity. Yet, he suspects that he will submit a renewal application on February 2017. He will likely be submitting a proposal for structured and elaborate evaluation of Open Knee(s) models. Ahmet and Jason are also interacting with other knee researchers to submit a proposal for the explorations of data exchange and model reproducibility. He also mentioned knee data provided by other researchers including those data sets pros an cons when compared to Open Knee(s).