Recurring Meeting of Cleveland Clinic Core Team

Date: December 20, 2016

Time: 10:30 AM EST

Means: In person meeting

Attendees:

1. Ahmet Erdemir
2. Snehal Chokhandre
3. Robb Colbrunn
4. Tara Bonner

Agenda:

1. Discuss immediate action items from the last meeting.
2. Discuss progress of tissue testing protocol evaluation.
3. Discuss segmentation progress.
4. Decide immediate action items for the next meeting.
5. Other.

Ongoing Action Items:

• Ahmet
  • Write progress report for the Advisory Report meeting.
  • Complete reviewing the drafts of data manuscripts.
• Snehal
  • Continue filling in the dashboard for tissue testing reproducibility.
• All
  • Continue segmentation based on commitments listed in the Roadmap.

Notes:

1. Discuss immediate action items from the last meeting.
   • Most action items were related to the ongoing agenda items; refer to discussions below.
2. Discuss progress of tissue testing protocol evaluation.
   • Snehal prepared a larger rectangular sample of meniscus, only by manually cutting it with a scalpel; without punching a cylindrical sample. She minimized soaking of the larger sample before testing and marked the sides of the sample. She conducted the test using the standard protocols (unconfined, 5-15% pre-conditioning at 1000 cycles at 2 Hz than up to 15% strain stress-relaxation test) and immediately took the sample out and refrigerated for two hours. She put back the sample and re-did test without remueasuring thickness). Repeatability improved, e.g. max error less than 10%. The next day she prepared another large sample and tested the same way; except she remeasured and incorporated the new thickness in between tests.
3. Discuss segmentation progress.
4. Decide immediate action items for the next meeting.
   • See Ongoing Action Items above.
5. Other.