In an effort to narrow down the Ten Simple Rules of Credible Practice of M&S in Healthcare as seen by the "Practice Standards and Guidelines" community, I propose the following steps: 1. Start by providing a 1-3 sentence description of what the following list of rules mean to us. You are not require...

Slide 7: Need, under Clinical Urgency: - Change the first bullet From: * There is a pressing need to utilize computational modeling & simulation to support clinical research and decision making in healthcare. To : * Modeling and simulation offers the capabilities to potentially expedite and increas...

Jacob, Thanks a lot for taking the point on this. See below for my concurrences, reservations, and recommended alternative changes. Slide 7: add Engineering before mathematical Slide 8: add especially before complicated Agreed these two changes Slide 8: extend uncertainty estimation by adding and pr...

Definition for "multiscale model." Is there some papers or reference information on this topic? ... perhaps that justify having various levels of abstraction in M&S? Multiscale modeling has become pretty common thing these days. In fact Digital Astronaut and a few other groups within NASA have been...

Hi all, Regarding individual entries vs phrases, I like the Jacob's three step process and I agree with Martin that relying only definition of individual words can lead to people inferring their own definition. So I am also in favor of clearly defining phrases as well as individual words. I think th...

Ahmet, Martin Steel posed a good question that prompted me to suggest that we define Multiscale Model or Multiscale Modeling so that we are all on the same page. I think a good place to start is with the definition IMAG uses: "Multiscale biomedical modeling uses mathematics and computation to repres...

Hi Martin, I just noticed that I had forgotten to the following questions. Can we get this document to assist/inform our purpose? It is not available for wider distribution yet. But I will make sure you get a copy as soon as it is. It would be helpful to see a definition for this term "multiscale mo...

Hi Ahmet, This is a great list you and Gary have started. I have learned that some confusions can arise when suing the flowing terms. Qualitative and Quantitative - fore example quantitative vs qualitative V&V Formal and Informal - fore example formal vs informal uncertainty quantification First pri...

Jeff, RE: distinguish the deliverables from similar deliverables that are out there already or are under preparation by other groups with similar interests (ASME V&V40, for example). Although there might be some overlaps between ASME and CPMS deliverable, the deliverable of this CPMS will be differe...

"in-silico"? This is the 1st time I'm exposed to this word - makes me think we're growing something in a petri dish with a silicon base (ever here of a Horta?) To be technically accurate, I'd want to avoid this term, which means it will probably ... (insert biological-humor sub-routine) ... go vira...