Treat­ment de­sign for mus­cu­loskele­tal dis­or­ders us­ing in sil­ico pa­tient-spe­cific dy­namic sim­u­la­tions is be­com­ing a clin­i­cal pos­si­bil­ity. How­ever, these sim­u­la­tions are sen­si­tive to model pa­ra­me­t