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partition function estimates up to a multiplicative constant

Posted: Wed Oct 09, 2013 1:08 am
by ponadto
Hello,

WHAM allows you to get partition functions up to a multiplicative constant. For example, the ratio Z(T_1)/Z(T_2) is correct, but Z(T_1) - not quite.

My question: does anyone know a way of estimating Z(T_1) "precisely"? Or, although I doubt it, maybe MBAR has this feature?

Cheers,
Maciek