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We only have one force plate and motion capture data for the lower extremity. Will static optimization (SO) work if I only apply force to one leg?

Hi, it depends on your movement. For walking, SOpt works pretty well for the entire stride of that leg.

Hello , Mohammadreza Rezaie
Yes its for walking.
I'm attempting to estimate joint reaction load but getting an unexpected estimate of knee joint load.
I suppose a one-leg model is required. Please help.

Removing the other leg doesn't affect your results. Knee joint contact force estimation is still one of the challenges in biomechanics. By including more muscle properties such as tendon elasticity and muscle volume in your analysis, you may get a better estimation. Please find these references:

- viewtopic.php?f=91&t=14556&p=42087&star ... a80#p42064
- https://github.com/stanfordnmbl/MatlabS ... timization
- Zargham et al. (2019). Inverse dynamic estimates of muscle recruitment and joint contact forces are more realistic when minimizing muscle activity rather than metabolic energy or contact forces. Gait & posture, 74, 223-230.
- Kaneda et al. (2023). Can static optimization detect changes in peak medial knee contact forces induced by gait modifications?. Journal of Biomechanics, 152, 111569.
- Uhlrich et al. (2022). Muscle coordination retraining inspired by musculoskeletal simulations reduces knee contact force. Scientific Reports, 12(1), 9842.