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Cervical Spine Injuries: A Whole-Body Musculoskeletal Model for the Analysis of Spinal Loading. PLOS ONE. 4 Jan 2017. Dario Cazzola , Timothy P. Holsgrove, Ezio Preatoni, Harinderjit S. Gill, Grant Trewartha (2017)  View

Cervical spine trauma from sport or traffic collisions can have devastating consequences for individuals and a high societal cost. The precise mechanisms of such injuries are still unknown as investigation is hampered by the difficulty in experimentally replicating the conditions under which these injuries occur. We harness the benefits of computer simulation to report on the creation and validation of i) a generic musculoskeletal model (MASI) for the analyses of cervical spine loading in healthy subjects, and ii) a population-specific version of the model (Rugby Model), for investigating cervical spine injury mechanisms during rugby activities. The musculoskeletal models were created in OpenSim, and validated against in vivo data of a healthy subject and a rugby player performing neck and upper limb movements. The novel aspects of the Rugby Model comprise i) population-specific inertial properties and muscle parameters representing rugby forward players, and ii) a custom scapula-clavicular joint that allows the application of multiple external loads. We confirm the utility of the developed generic and population-specific models via verification steps and validation of kinematics, joint moments and neuromuscular activations during rugby scrummaging and neck functional movements, which achieve results comparable with in vivo and in vitro data. The Rugby Model was validated and used for the first time to provide insight into anatomical loading and cervical spine injury mechanisms related to rugby, whilst the MASI introduces a new computational tool to allow investigation of spinal injuries arising from other sporting activities, transport, and ergonomic applications. The models used in this study are freely available at and allow to integrate in silico analyses with experimental approaches in injury prevention.

Related Publications
DEVELOPMENT OF A MUSCULOSKELETAL MODEL FOR THE ANALYSIS AND SIMULATION OF CERVICAL SPINE LOADING DURING RUGBY ACTIVITIES. Dario Cazzola, Ezio Preatoni, Timothy Holsgrove, Richie Gill, Grant Trewartha. XXV Congress of the International Society of Biomechanics, Glasgow; 07/2015 (2015)  View