Models and simulations of human function impact medicine and medical technology. Particularly, musculoskeletal modeling provides an avenue for insight into the human body, which might not be otherwise possible. However, reaching the ultimate goal of functional multi-scale human models has been slowed by the lack of freely available datasets of anatomical models and geometries. Moreover, female-specific geometries have been neglected with a widespread emphasis on male geometry. To help realize this goal, we have developed and shared complete three-dimensional musculoskeletal geometries extracted from the National Libraries of Medicine Visible Human Female and Male cryosections. Muscle, bone, cartilage, ligament, and fat from the pelvis to the ankle were digitized and exported. These geometries provide a foundation for continued work in human musculoskeletal simulation with high-fidelity deformable tissues that enable a better understanding of normal function and the evaluation of pathologies and treatments. This work is novel as it includes both the male and female Visible Human specimens, outputs at multiple levels of post-processing for maximum data reuse, and is publicly available.
Complete 3D musculoskeletal geometries were extracted from the National Libraries of Medicine Visible Human Female and Male cryosection images. Muscle, bone, cartilage, ligament, and fat from the pelvis to the ankle were digitized and exported in shareabl
Complete 3D musculoskeletal geometries were extracted from the National Libraries of Medicine Visible Human Female and Male cryosection images. Muscle, bone, cartilage, ligament, and fat from the pelvis to the ankle were digitized and exported in shareable formats and made available for download. While a substantial amount of published work has been derived from the Visible Human Project, this is the first time a large number of musculoskeletal 3D geometries are being made available to the public including both male and female specimens. Currently, 260 geometries from the Visible Human Male and Female are available consisting of 76 muscles, 28 bones, 16 cartilages, 8 ligaments, and 2 fat geometries per subject. The library is available at multiple layers of processing and remarkably in a final form with no overlap between individual structures. This library is made available to motivate continued work in multi-scale, high-fidelity musculoskeletal modeling and promote reuse and continued development of the dataset.
This data was made possible by NIH grant U01 AR072989 with combined support from the National Institute for Arthritis, Musculoskeletal, and Skin Diseases (NIAMS), the National Institute of Biomedical Imaging and Bioengineering (NIBIB), and the National Institute of Child Health and Human Development (NICHD).
Andreassen, T.E., Hume, D.R., Hamilton, L.D. et al. Three Dimensional Lower Extremity Musculoskeletal Geometry of the Visible Human Female and Male. Sci Data 10, 34 (2023). https://doi.org/10.1038/s41597-022-01905-2.
Andreassen, T. E., Hume, D. R., Hamilton, L. D., Higinbotham, S. E. & Shelburne, K. B. An Automated Process for 2D and 3D Finite Element Overclosure and Gap Adjustment using Radial Basis Function Networks. 1–13 (2022) doi: https://doi.org/10.48550/arXiv.2209.06948
TE Andreassen, DR Hume, LD Hamilton, SE Higinbotham, KB Shelburne (in review) “An Automated Process for 2D and 3D Finite Element Overclosure and Gap Adjustment using Radial Basis Function Networks,” Computer Methods and Programs in Biomedicine Update, 2023.
260 geometries from the Visible Human Male and Female were extracted from the imaging datasets. The skeletal components consist of the pelvis through the feet; the ligament and cartilage components consist of hip, knee, and ankle cartilages and knee ligaments; muscle components consist of 76 separate muscles from the Iliacus proximally to the Flexor Digitorum distally; and two fat components consisting of the intramuscular fat and fascia, and the outer fat, dermis, and epidermis.See all Downloads