In the File menu, there are several save options:

How to use these save options:

  1. Launch Slicer from the directory where you would like to save the label maps, .xml files, and models.
  2. Load the data that you want to segment, and select values for viewing, such as FOV.
  3. Use Save Scene As to save an .xml file with a specific name.
  4. Use Save Scene with Options to save the scene with your selected options.
  5. Begin segmentation. Save the label maps.
  6. Use Save Scene with Options to save the scene.
  7. Any time that you change and save the label maps, use Save Scene with Options to save the scene.