TF ID	Rule	Comments 1	Comments 2	Comments 3	Comments 4
Surplus_FDP	( not ( FBP[c] > 0  and not ( TKTA2R[c] < 0 or TKTB2R[c] < 0 or TALAR[c] < 0 or TALBR[c] < 0 or PGIR[c] > 0 ) ) ) or FRU[media] > 0	* Ewb update for direction change of rxn			
Surplus_PYR	not ( MAEB[c] > 0 or SFCA[c] > 0 ) and not ( GLCPTS[t] > 0 or PYKF[c] > 0 or PFKA[c] > 0 or PYKA[c] > 0 or DLD1R[c] < 0 or DLD2[c] > 0 or DCTA1[t] > 0 or DCUA1[t] > 0 or DCUB1[t] > 0 )				
CRP_GLCN	GLCN[media] > 0				
CRP_noGLCN	not ( GLCN[media] > 0 )				
CRP_noGLC	not ( GLCN[media] > 0 or GLC[media] > 0 )				
CRP_noARAB	not ( GLCN[media] > 0 or GLC[media] > 0 or ARAB[media] > 0 )				
CRP_noXYL	not ( GLCN[media] > 0 or GLC[media] > 0 or ARAB[media] > 0 or XYL[media] > 0 )				
CRP_noRIB	not ( GLCN[media] > 0 or GLC[media] > 0 or ARAB[media] > 0 or XYL[media] > 0 or RIB[media] > 0 )				
CRP_noMAL	not ( GLCN[media] > 0 or GLC[media] > 0 or ARAB[media] > 0 or XYL[media] > 0 or RIB[media] > 0 or MAL[media] > 0 )				
CRP_noGL	not ( GLCN[media] > 0 or GLC[media] > 0 or ARAB[media] > 0 or XYL[media] > 0 or RIB[media] > 0 or MAL[media] > 0 or GL[media] > 0 )				
CRP_noGLT	not ( GLCN[media] > 0 or GLC[media] > 0 or ARAB[media] > 0 or XYL[media] > 0 or RIB[media] > 0 or MAL[media] > 0 or GL[media] > 0 or GLT[media] > 0 )				
CRP_noLAC	not ( GLCN[media] > 0 or GLC[media] > 0 or ARAB[media] > 0 or XYL[media] > 0 or RIB[media] > 0 or MAL[media] > 0 or GL[media] > 0 or GLT[media] > 0 or LAC[media] > 0 )				
CRP_noMAN	not ( GLCN[media] > 0 or GLC[media] > 0 or ARAB[media] > 0 or XYL[media] > 0 or RIB[media] > 0 or MAL[media] > 0 or GL[media] > 0 or GLT[media] > 0 or LAC[media] > 0 or MAN[media] > 0 )				
CRP_noSUCC	not ( GLCN[media] > 0 or GLC[media] > 0 or ARAB[media] > 0 or XYL[media] > 0 or RIB[media] > 0 or MAL[media] > 0 or GL[media] > 0 or GLT[media] > 0 or LAC[media] > 0 or MAN[media] > 0 or SUCC[media] > 0 )				
Crp	b3357				
GlpR	b3423
GntR	b3438
RbsR	b3753
IlvY	b3773
TdcR	b3119
MalT	b3418
XylR	b3569
UhpB	b3668
AsnC	b3743
GlnB	b2553
GlnD	b0167
GlnG	b3868
GlnL	b3869
NRI_low	GlnG and GlnB and GlnD
NRI_hi	NRI_low and RpoN
RhaS	b3905
RhaR	b3906
CpxR	b3912
CytR	b3934
SoxR	b4063
MelR	b4118
ArcA	b4401 and not ( O2[media] > 0 )
Cra	b0080
DcuS	b4125
DcuR	b4124
FadR	b1187
Fnr	b1334 and  not ( O2[media] > 0 ) 
GalR	b2837
GalS	b2151
IclR	b4018
LacI	b0345
Mlc	b1594
PdhR	b0113
RpiR	b4089
RpoN	b3202
Nac	b1988
Lrp	b0889
ArgR	b3237
MetJ	b3938
CadC	b4133
MetR	b3828
CysB	b1275
TyrR	b1323
TrpR	b4393
PurR	b1658
XapR	b2405
DeoR	b0840 and not ( DEOB1R[c] > 0 or DEOB1R[c] < 0 )
AtoS	b2219
AtoC	b2220
FadR2	not ( C140[media] > 0 or C160[media] > 0 or C180[media] > 0 ) 
CitA	b0619
CitB	b0620
FeaR	b1384
CynR	b0338
CaiF	b0034
NarL	b1221 and ( NO3[media] > 0 or NO2[media] > 0 )
ExuR	b3094
UxuR	b4324
KdgR	b1827
AllR	b0506
AllS	b0504
SdaR	b0162
HcaR	b2537
MhpR	b0346
TorS	b0993
TorR	b0995 and TorS
IdnR	b4264
YiaJ	b3574
OxyR	b3961 and ( H2O2[media] > 0 or O2[media] > 0 )
PhoR	b0400
PhoB	b0399
GlcC	b2980
FhlA	b2731
AppY	b0564
NagC	b0676
GutR	b2707
RpoS	b2741
TreR	b4241
FucR	b2805
AraC	b0064
Fis	b3261
SoxS	b4062
BetI	b0313
BirA	b3973
Cbl	b1987
DsdC	b2364
Fur	b0683
GcvA	b2808
GcvR	b2479
KdpD	b0695
KdpE	b0694
MalI	b1620
NhaR	b0020
FeaB	b1385
MarA	b1531
NadR	b4390
OmpR	b3405
Rob	b4396
RpoE	b2573 and heat_shock[stim] 
GatR	b2090 and b2087
LysR	b2839
AdiY	b4116
GutM	b2706
MtlR	b3601
TdcA	b3118
UhpA	b3669
Growth	BIOMASS[a] > 0