Webinar
How to Ensure Quantitative Systems Pharmacology Model Quality – Introducing the Model Qualification Method
We invite you to join us for an introduction to the methods that Rosa and Co. have developed and effectively used to assess the quality of their quantitative systems pharmacology models.
Speaker: Christina Friedrich, Rosa & Co.
Time: Tuesday, March 6, 2018 at 9:00 a.m. PST
Registration: Registration is free but is required. Click here to register.
Abstract: Quantitative Systems Pharmacology (QSP) modeling considers drug mechanism of action in the context of biological disease mechanisms to improve understanding of human biology and pharmacology. QSP models differ from pharmacokinetic/pharmacodynamic models in their purpose and data requirements, and there can be significant variability among QSP models in depth and breadth, specific research questions, and available data. Because of these differences, traditional prescriptive model validation approaches are neither appropriate nor sufficient. An alternative approach for ensuring QSP model quality is needed. The Model Qualification Method (MQM) offers a general and customizable framework for ensuring QSP model quality, including consideration of scope and relevance, uncertainty, variability, and comparison to data. This webinar will introduce MQM and present two case studies from Rosa’s practice to illustrate the utility of the method.
Participating in the Webinar: Make sure that your computer meets the minimum requirements for running the webinar software. For an overview of the webinar interface and additional instructions on participating, please consult our webinar guide.