• 2024-09-10

Collaborators Meeting

Date: Sept 10, 2024

Time: 4:00 PM US/Eastern

Means: MS Teams

Attendees:

1. Jason Halloran (WSU)
2. Carl Imhauser (HSS)
3. Peter Laz (DU)
4. Snehal Chokhandre (CC)
5. Nancy Kim (ABI)
6. Maryam Nazem (DU)

Agenda:

1. Discuss pending tasks for Kneehub parent grant
2. Discuss manual literature search
3. Discuss preparation for Delphi study
4. Discuss initiation of end to end implementation for one context of use based on core team consensus
5. Other

Immediate Action Items:

• Snehal
  • Set up weekly meetings for context of use confirmation and developing implementation strategies based on core team consensus
  • Send sets of articles to team members for review
• Maryam and Peter
  • Start exploring Thor A's code for data conversion
• Peter, Maryam, Nancy, Kate
  • Clean up benchmarking data (reach out to teams for information, if needed)
• Carl
  • Provide link to benchmarking package
• Jason and Carl
  • Complete reuse case
• All
  • Go over model development specifications from all teams to start core team consensus discussions

Notes:

1. From the ongoing literature review and Delphi study plan development, it appears that the process will take longer than initially anticipated. To utilize the award time more efficiently, Ahmet suggested the core team should identify one context of use and decide specifications that will be used by two teams to implement the end to end workflow. Snehal and Jason communicated the need to the team and there is a consensus among the team. As of now, the identified context of use is modeling intact, ACL deficient and ACL reconstructed knee under various loading conditions. HSS and DU both have relevant mechanical data.
2. The team will meet weekly until the context of use and foundational data are identified and end to end workflows are agreed upon (for all phases). Details about the tools, granularity of specifications etc. will be decided upon.
3. Pete suggested the process should be broken up in phases, so while work is ongoing on one phase, specifications for the next phase can be built/agreed upon.
4. May reach out to Nico Verdonschot for some guidance on Delphi preparation. The team has consulted with two teams of experts (Cobus Muller + Mo Saffarini and Manuela Molina), however, compensation for foreign consultants can be an issue.
5. Work on the benchmarking paper is ongoing. Spreadsheets are being populated to be able to overlay profiles for different loading scenarios for both the oks and natural knee. Thor A has developed scripts for the calibration paper to convert each of the teams data to the right coordinate systems/transformations back to the original data set etc. that can help support the process. Maryam will start familiarizing herself with the scripts.
6. The distribution of work will be decided in the upcoming meetings.
7. Jason's group is working on a modeling tool to take segmentations and create mesh models, create boundary conditions and run the model from a config file. If the translators are written, models can be created for different solvers. This may be a useful resource for the team.
8. Next month will be utilized to clean up the benchmarking data and prepare to start consensus conversations in the following weeks.
9. Snehal described the current state of literature review for initial identification of contexts of use. Along with the initial 280 articles identified from 4 databases, articles based on citation metrics (total citations and average citations) from Google Scholar were also identified. 20 articles for each metric and search term combinations were identified for a total of 280. An initial frequency of terms search using ChatGPT indicates TKA and meniscal injuries or pathologies were the most common clinical contexts. Snehal will send some articles sets to the team for help with reviews.