Recurring Meeting of Cleveland Clinic Core Team
Date: October 15, 2013
Time: 10:30 AM EST
Means: In person meeting
Attendees:
- Ahmet Erdemir
- Jason Halloran
- Craig Bennetts
- Snehal Chokhandre
- Robb Colbrunn
Agenda:
- Review assigned tasks
- Discuss specifications development progress
- Action items for following week
- Other
Notes
1 and 2. Review assigned tasks and discuss specifications development progress
- All the assigned tasks were discussed and progress was reviewed.
- Specimen specifications:
- Snehal started updating the relevant page. Number of specimens and inclusion criteria was included.
- Ahmet suggested adding more specimens that will be low priority but can be added to the data set if resources permit doing so.
- Jason suggested NDRI might be another source for acquiring knees and will be contacting the NDRI representative.
- Pre and during procedure evaluation of specimens was discussed. If needed knees can be obtained from the surgical skills lab and will be screened for existing osteoarthritis.
- Defects can be created artificially if diseased specimens are not obtained.
- Alternatives, potential bottlenecks etc will be included in the specifications page.
- Version and numbering was discussed. Specimen gender, age etc will not be included in the numbering.
- Ahmet suggested adding sub sample description for tissue testing.
- Specimens will be numbered as 001, 002 etc.
- Specimens will be requested to include from hip to ankle.
- Specimen specifications are 50% complete will be completed by next meeting and specimens will be ordered.
- Imaging specifications:
- Jason, Craig and Snehal met to discuss the specifications. The brass registration market set up that may be used was observed to add noise/ artefact to the imaging data.
- MRI imaging specifications from previous studies will be built upon.
- Jason and Ahmet will meet Chris on October 28th to discuss the specifications and requirements further.
- For now the previously used spherical markers will be used and if issues with the patella registration phantom are not resolved, some other material might be considered for markers.
- The page will be updated with all the available informations and improved after the meeting.
- Robotics testing specifications:
- The team met to discuss the requirements.
- Ahmet provided an outline and comments for information organization.
- File naming and specimen naming conventions need to be decided.
- A pulling test at different flexion angles to get ligament in situ strain related information might be added to the tibiofemoral joint testing protocol conditions (can be added as secondary conditions).
- Conditions: testing scenarios, measurements : what is obtained.
- To avoid issues related with inverting the specimen in the testing set up, tibiofemoral and patellofemoral joint tests will be performed separately (registration will be redone).
- Specimen dissection will be added to specimen preparation ( if more details are added a separate page will be made).
- Flowchart of order of operations will be added to specifications main page.
- Tekscan specifications will be added to robotics testing and infrastructure.
- An advisory board meeting might be scheduled for the end of October.
- FEBio feature request:
- Jason and Ahmet met and discussed the feature requests to FEBio that directly relate to Open Knee. A list of requests based on priority was created by Jason and details will be populated in the coming days.
- Test problems and estimated completions will be requested.
- Tissue testing specifications:
- Tara and Snehal met and discussed the tissue testing details.
- Some samples will be tested again (pilot) to ensure the errors noticed in previous data sets can be avoided.
- Primary and secondary sample locations will be identified.
- Primary samples will be tested as a priority.
- One sample from each tissue will be set as a priority to build required constitutive model.
- Zonal, regional etc data will be included as secondary information.
- Primary samples: ACL, PCL, MCL, LCL, Menisci, medial and lateral femoral and tibial cartilage, patellar cartilage, cartilage in femoral groove,capsule, patellar ligament, quadricep tendon. (secondary : MPFL)
- Secondary samples will be prepared along with the primary samples and frozen for later use.
- More stress relaxation stages will be added and a slower strain rate (ramp loading) will be used. This might reduce the overall test time.
- Test workflow for cloud computing prototype
- Craig and Ahmet met to discuss the features of the requested supercomputing gateway (to be developed by Stanford group).
- Repository will contain different models and users can use a config file which can apply different parameters to the model and run simulations.
- The interface will allow selection of model, uploading a configuration file and submit it to the supercomputer and get results.
- Initially simple models such as a small square representing cartilage simulated under compression can be used to develop the gateway.
- Craig will develop the specifications.
3. Action items for following week
- Team members will continue to update the tasks based on assigned priority end dates.
4. Other
- Ahmet added documentation task for FEBio summary and mechanical experimentation infrastructure.
- Equipment and resources including website links will be added to the document.
- Ahmet updated the grant information. The grant is available for public viewing and includes the data sharing and software sharing plans.