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  * TBD   * As most of the group was at WCB last week, the immediate action items will be carried over for this week.
  * Katie gave an update on her progress creating ACL/PCL solid models and meshes. The process has been documented on the wiki for her project, "cruciate modeling." Salome was used to create a tetrahedral mesh. Ahmet will likely port the relevant documentation to the Open Knees wiki.

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  * TBD   * Robb will be out of town the beginning of next week. The testing will likely move forward without his presence, at least until he returns.
  * The whole open knee process will be the focus. The test knee will be taken out of the freezer Sunday afternoon. Specimen preparation will start Monday afternoon, MRI on Tuesday morning and tibiofemoral testing on Tuesday afternoon. Patellofemoral testing will follow on Wednesday morning with tissue specimen preparation starting on Wednesday afternoon.
  * The group discussed retaining a peripheral tissue sample from an untested region (e.g. the foot) for reference tissue testing. If subject to the same treatment as the whole specimen, that is the same hydration and freeze and thaw cycles, the tissue may reflect the overall level of tissue degradation. The candidate tissue may be a cartilage sample (with the bone) from the ankle joint. The whole foot will be retained and the cartilage sample tested everyday throughout the whole protocol. A simple compression test may suffice for this purpose.
  * Pressure sensors need to be calibrated and equivalenced. Robb and Jason will accomplish that this week. Related specifications will need to be populated, including what computer and hardware will need to be used.
  * Snehal will remove the knee from the freezer on Sunday at an appropriate time (see specifications).
  * Tara will take care of specimen preparation on Monday.
  * Craig will take the lead on MRI specimen preparation.
  * Tara will lead the specimen potting and tibiofemoral testing. The related trajectories will be created before next week. Gravity compensation will also be taken care of this week. One related concern that Ahmet brought up is the reproducibility of the testing. Robb noted the compensation also includes machine effects, including friction induced by the mechanical setup. One option to overcome this issue is to mount the tibia up for the tibiofemoral testing and reverse the knee for the patellofemoral testing only. The patellofemoral testing only needs a passive flexion cycle. It was decided inverting the knee for tibfem testing is the best way to go.
  * Katie will be in charge of taking pictures and documentation of how the protocols are followed, as well as changes to specifications as they are determined.
  * Helpers for each task were decided on.
  * Pilot testing data will populate the OKS004 (or lower if the specimen has not been bought yet), in which the metadata will describe this as a pilot test. Snehal will verify what specimens we currently have.
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  * TBD   * Action items were assigned and agreed upon by the group. See Immediate Action Items above.
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  * TBD   * Ahmet gave an overview of his meeting with Stanford Univ and Univ of Utah groups at the WCB.

Recurring Meeting of Cleveland Clinic Core Team

Date: July 15, 2014

Time: 10:30 AM EST

Means: In person meeting

Attendees:

  1. Ahmet Erdemir
  2. Jason Halloran
  3. Craig Bennetts
  4. Snehal Chokhandre
  5. Katie Stemmer
  6. Robb Colbrunn
  7. Tara Bonner

Agenda:

  1. Discuss immediate action items from the last meeting.
  2. Discuss pilot testing preparation (to be scheduled between July 21st-25th) .
  3. Decide immediate action items for the next meeting.
  4. Other.

Immediate Action Items:

  • Craig
    • Review specimen preparation specifications.
  • Tara
    • Finalize gravity compensation for robotics testing of joints.
  • Katie
    • Review specimen preparation and tissue testing specifications.
  • Snehal
    • Complete and test Python script for down sampling of video data.
  • Robb and Snehal
    • Evaluate processing tools to move between "right knee abstraction" and "physical representation" on previously collected data (save the day).
  • Jason and Robb
    • Finalize processing tools to move between "right knee abstraction" and "physical representation" as a long term solution.

Notes:

  1. Discuss immediate action items from the last meeting.
    • As most of the group was at WCB last week, the immediate action items will be carried over for this week.
    • Katie gave an update on her progress creating ACL/PCL solid models and meshes. The process has been documented on the wiki for her project, "cruciate modeling." Salome was used to create a tetrahedral mesh. Ahmet will likely port the relevant documentation to the Open Knees wiki.
  2. Discuss pilot testing preparation (to be scheduled between July 21st-25th) .
    • Robb will be out of town the beginning of next week. The testing will likely move forward without his presence, at least until he returns.
    • The whole open knee process will be the focus. The test knee will be taken out of the freezer Sunday afternoon. Specimen preparation will start Monday afternoon, MRI on Tuesday morning and tibiofemoral testing on Tuesday afternoon. Patellofemoral testing will follow on Wednesday morning with tissue specimen preparation starting on Wednesday afternoon.
    • The group discussed retaining a peripheral tissue sample from an untested region (e.g. the foot) for reference tissue testing. If subject to the same treatment as the whole specimen, that is the same hydration and freeze and thaw cycles, the tissue may reflect the overall level of tissue degradation. The candidate tissue may be a cartilage sample (with the bone) from the ankle joint. The whole foot will be retained and the cartilage sample tested everyday throughout the whole protocol. A simple compression test may suffice for this purpose.
    • Pressure sensors need to be calibrated and equivalenced. Robb and Jason will accomplish that this week. Related specifications will need to be populated, including what computer and hardware will need to be used.
    • Snehal will remove the knee from the freezer on Sunday at an appropriate time (see specifications).
    • Tara will take care of specimen preparation on Monday.
    • Craig will take the lead on MRI specimen preparation.
    • Tara will lead the specimen potting and tibiofemoral testing. The related trajectories will be created before next week. Gravity compensation will also be taken care of this week. One related concern that Ahmet brought up is the reproducibility of the testing. Robb noted the compensation also includes machine effects, including friction induced by the mechanical setup. One option to overcome this issue is to mount the tibia up for the tibiofemoral testing and reverse the knee for the patellofemoral testing only. The patellofemoral testing only needs a passive flexion cycle. It was decided inverting the knee for tibfem testing is the best way to go.
    • Katie will be in charge of taking pictures and documentation of how the protocols are followed, as well as changes to specifications as they are determined.
    • Helpers for each task were decided on.
    • Pilot testing data will populate the OKS004 (or lower if the specimen has not been bought yet), in which the metadata will describe this as a pilot test. Snehal will verify what specimens we currently have.
  3. Decide immediate action items for the next meeting.
    • Action items were assigned and agreed upon by the group. See Immediate Action Items above.
  4. Other.
    • Ahmet gave an overview of his meeting with Stanford Univ and Univ of Utah groups at the WCB.

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