Recurring Meeting of Cleveland Clinic Core Team

Date: August 26, 2014

Time: 10:30 AM EST

Means: In person meeting

Attendees:

1. Ahmet Erdemir
2. Craig Bennetts
3. Snehal Chokhandre
4. Robb Colbrunn
5. Tara Bonner

Agenda:

1. Discuss immediate action items from the last meeting.
2. Discuss data acquisition progress for oks004.
3. Decide immediate action items for the next meeting.
4. Other.

Immediate Action Items:

• Robb
  • Provide readme files for joint mechanical testing data indicating file types and a general description of what different file types contain (ideally in an automated fashion)
  • Recalibrate pressure sensor used in oks004 to ensure its repeatability.
  • Update pressure calibration wiki page to describe specifics of calibration.
• Tara
  • Check optimized joint coordinate system alignment with tibia coordinate system to evaluate anterior-posterior axis orientation and anterior-posterior laxity curves.
• Craig
  • Separate MR images into relevant sequences for ease of use and access.
  • Commit video data reduction script to the utilities folder in the source code repository.
• Snehal
  • In a readme file, provide the link for the MR image renaming code, including a summary of licensing.
  • Evaluate if video data collection is needed for unconfined compression of cartilage and meniscus samples.
  • Ask Martin Garon of Biomomentum Inc. to provide a demonstration of camera and displacement/load data synchronization.
  • Troubleshoot the system to evaluate if video collection causes software crash.
• Ahmet
  • Conduct a trial test with video collection using separate ramp/hold commands.
• All
  • Review and finalize oks004 joint testing notes.

Notes:

1. Discuss immediate action items from the last meeting.
   • Robb will add readme files in Midas for previously acquired mechanical testing data. The readme files will describe the file types and data in the files.
   • Tara plotted the tibiofemoral joint mechanical testing data to evaluate the data quality. AP laxity data showed unexpected translations, i.e., translations towards the opposite direction of the applied force. This may be a coordinate system related issue.
   • Robb will work on pressure sensor recalibration. He will also update the pressure sensor specifications.
   • Craig will rename MRI data for oks004 based on protocols and upload to Midas.
   • Snehal will upload the DICOM renaming Matlab script to the utilities folder in source code repository. She needs to make sure license of the original code is appropriate for dissemination.
2. Discuss data acquisition progress for oks004.
   • Snehal has been working on acquiring tissue testing data for oks004. All the necessary protocols are programmed in the system. Twenty-one tests were complete. Compression tests went without any issues. Tensile testing initially worked except jumps were still noticed in displacement data. The software crashed several times in the last tension tests. Snehal contacted Martin Garon from Biomomentum Inc. regarding these Mach-1 issues. Martin speculated that video capture might be causing all the errors. Snehal will perform trial tests with and without video capture to evaluate this speculation. Martin also suggested using RAW video files instead of BMP to save space.
   • Snehal will look for articles to make sure Poisson's ratio calculation can be done using Young's and aggregate moduli and in return, video data is not required for compression tests.
   • It was also decided that ramp and hold cycles will be separated in the testing protocols to have a better control over data (mainly video) acquisition frequency. Force/displacement and video data synchronization also needs to be confirmed for Mach-1.
   • One challenge in tissue testing is preparing flat cartilage samples for tensile testing. The curvature of the tissue does not always allow an easy sample preparation.
3. Decide immediate action items for the next meeting.
   • Action items were assigned to and agreed upon by the team. See Immediate Action Items above.
4. Other.
   • None noted.