Recurring Meeting of Cleveland Clinic Core Team

Date: June 9, 2015

Time: 10:30 AM EST

Means: In person meeting

Attendees:

1. Ahmet Erdemir
2. Craig Bennetts
3. Snehal Chokhandre
4. Callan Gillespie
5. Omar Gad
6. Connor Lough
7. Diana Suciu

Agenda:

1. Discuss immediate action items from the last meeting.
2. Discuss oks008 testing/ data.
3. Progress on summer internship projects.
4. Decide immediate action items for the next meeting.
5. Other.

Immediate Action Items:

• Ahmet
  • Disseminate oks008 MR image sets.
  • Create specifications page for analysis of patellofemoral contact pressures.
• Craig
  • Meet with summer students to go over convergence optimization wiki and describe workflow.
  • Provide sample MR images for oks008 in the relevant wiki page.
• Snehal
  • Continue interacting up with Biomomentum, Inc. about mechanical testing system tuning features.
  • Complete the structured testing plan for tuning the system for different sample sizes, strain levels and strain rates.
  • Fill in dissection and preparation information for tissue mechanics section for oks008 in the relevant wiki page.
• Robb
  • Conduct post-experiment calibration of pressure sensor used for oks008 testing.
• Tara
  • Provide laxity plots for oks008 in the relevant wiki page.
• Connor
  • Update registration related scripts to transform coordinates on spheres to local bone Optotrak marker coordinate systems.
  • Write a script to read STL files representing surfaces of registration markers and to fit a sphere to the data set.

  • Document progress on registration related scripts on the wiki, at Specifications/Registration.

• Diana
  • Update scripts to finalize reading of CSV files containing contact pressure data collected during patellofemoral joint testing.
  • Implement calculation for calibration, averaging, peak pressure, contact area, contact force in scripts for the analysis of patellofemoral contact pressures.

  • Document progress on scripts for contact pressure analysis on the wiki, at Specifications/PressureAnalysis.

• Omar
  • Update scripts to finalize extraction of time windows of interest in tibiofemoral joint kinematics/kinetics data.
  • Start drafting analysis of reproducibility data (anterior-posterior laxity) collected during tibiofemoral joint testing.

  • Document progress on scripts for pre-processing of joint kinematics/kinetics on the wiki, at Specifications/ModelingKinematicsKinetics.

Ongoing Action Items:

• Ahmet
  • Dissemination of joint mechanics testing data.
  • Detail image segmentation specifications.
  • Prepare flowcharts to describe data flow for pre-processing of joint kinematics/kinetics data.
• Craig
  • Anatomical imaging manuscript.
  • Large-scale analysis of simulation parameters for convergence.
• Snehal
  • Pivot shift manuscript.

  • Cruciate ligament modeling & simulation.

  • Evaluate alternative tissue testing strategy.
• Robb
  • Patellofemoral joint experimentation manuscript.
• Tara
  • Tibiofemoral joint experimentation manuscript.

Notes:

1. Discuss immediate action items from the last meeting.
   • Ahmet met all the members of the advisory board and will update the meeting minutes on relevant Wiki page.
   • Craig is working on the presentation for SB3C.
   • Craig will also discuss convergence optimization workflow with students.
   • Snehal contacted Morgan Jones for dissection of oks008. The dissection went well and students got the opportunity to see the knee anatomy up close and had a good learning experience. The dissection was also video recorded and will be uploaded to Midas.
   • Snehal has updated the tissue testing plan and is currently testing out both the PID tuning software and the Mach-1 system to find the right protocol vs system capability combination.
   • Omar was able to plot channels for tibiofemoral experimentation data for the sample files Ahmet had provided. He will start working on the AP laxity data.
   • Ahmet will also disseminate oks008 imaging data. He is also working on understanding tdms file organization used for robotics testing. He will add an illustration to show data organization from experimentation.
2. Discuss oks008 testing/ data.
   • Testing of oks008 went well without much unexpected issues. Notes of any deviations etc. were added as testing progressed.
   • Craig will put sample images for oks008 on specimen wiki page.
   • Tara will provide sample laxity data for oks008 on specimen wiki page.
   • Robb will calibrate oks008 pressure sensor.
3. Progress on summer internship projects.
   • Connor will determine organization of data in global registration marker config files. He will work on transformation matrices acquired from registration markers. He will also convert experimental sphere (registration marker) coordinates to Optotrak coordinate systems.
   • Diana will work on obtaining contact area from pressure distribution, peak contact pressure and total contact force from the csv files of time history of patellofemoral pressure distribution.
4. Decide immediate action items for the next meeting.
   • See Immediate Action Items above.
5. Other.
   • Image segmentation was discussed. Students will start familiarizing themselves with Slicer 3D and ITKSnap.