• RecurringMeetings
• 2016-07-26

Recurring Meeting of Cleveland Clinic Core Team

Date: July 26, 2016

Time: 10:30 AM EST

Means: In person meeting

Attendees:

1. Ahmet Erdemir
2. Snehal Chokhandre
3. Tara Bonner
4. Connor Lough
5. Jason Halloran (Cleveland State University)
6. Will Zaylor (Cleveland State University)
7. Christina Pope (Cleveland State University)

Agenda:

1. Discuss immediate action items from the last meeting.
2. Discuss progress of tissue testing protocol evaluation.
3. Discuss progress of joint testing and imaging data manuscripts.
4. Discuss segmentation plan and progress.
5. Decide immediate action items for the next meeting.
6. Other.

Immediate Action Items:

• Ahmet
  • Complete reviewing the drafts of data manuscripts.
• Snehal
  • Continue the documentation of tissue testing reproducibility.
  • Work on reproducibility testing of confined compression.
  • Continue reproducibility testing of tension tests.
• Robb and William
  • Continue working on scripts to generate of aggregated contact pressure plots for patellofemoral joint manuscript and accommodate suggested changes.
• Connor
  • Continue updating specifications for comparison of geometries.
• All
  • Continue segmentation based on commitments listed in the Roadmap.

Notes:

1. Discuss immediate action items from the last meeting.
   • Most action items were related to the agenda items; refer to discussions below.
2. Discuss progress of tissue testing protocol evaluation.
   • Snehal checked if the noise would affect meniscus unconfined compression test when using high resolution, low range transducer. The data looked good.
   • Snehal has been conducting repeatability tests three times with 2 hours between tests. There were problems in confined compression tests. These indicated the need for a potentially higher initial contact force setting. Sample shape was also a concern, which may be caused by punching the sample. Ahmet recommended burring instead of punching. She will try cutting the sample before soaking. She will also try a slightly larger diameter fixture.
   • Tensile tests did not appear to be repeatable, the second and third tests were close to each other but the first was stiffer. The first test may have caused a tissue failure or clamp slip. The group recommended increasing the target strain level in pre-conditioning. Snehal will also increase the preload to 10 grams.
   • Snehal also conducted repeatability tests for stress-strain measurements, i.e. not necessarily force-displacement measurement repeatability without removing the specimen and resetting the displacement. She did not show the processed results; raw data seemed variable. Snehal needs to implement zero stress-strain identification for post-processing.
   • Ahmet recommended Snehal to test rubber samples for confined compressing and tension first; when successful, move on to tissue force-displacement reproducibility; and when successful move on to stress-strain reproducibility.
   • Snehal will also update the wiki on how to use the tools for testing and preparing samples.
3. Discuss progress of joint testing and imaging data manuscripts.
   • Ahmet has been working on the papers. He wrote all the abstracts and has been planning to work on them section by section to ensure a coherent representation.
   • For dissemination, Ahmet has thought about separating the data for the three papers and provide all the necessary information in the packages, including some documentation which is only available in the wiki.
4. Discuss segmentation plan and progress.
   • Connor should segment all bones and cartilage for oks002. Ahmet wants Connor to compare his geometries of bones and cartilage for oks001 to Craig's and write up his comparison strategy as an abstract. Ahmet also asked Connor to think about another project to identify the role of geometric uncertainties on mechanics predictions. He can use sets of cartilage segmentations for oks001; conduct a simple simulation, i.e. femur cartilage compressed on tibia, and compare contact pressure predictions between models from different segmentations of the same cartilage.
5. Decide immediate action items for the next meeting.
   • See Immediate Action Items above.
6. Other.
   • None noted.