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''' Weekly Update in lieu of Recurring Meeting of Cleveland Clinic Core Team'''
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'''Date:''' January 3, 2017
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''' Weekly update for Open Knees''' '''Provided by:''' Snehal Chokhandre
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'''Date: January 3rd,2017''' '''Ongoing Action Items:'''

 * Ahmet
  * Review drafts of data manuscripts for submission.
 * Snehal
  * Complete studies for tissue testing reproducibility.
  * Continue tissue testing of Open Knee(s) specimens.
 * All
  * Continue segmentation of Open Knee(s) specimens.
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1.   Tissue testing progress.

 * Snehal did additional repeatability tests for cartilage tensile test to increase confidence in the procedure and results. Two tests were done with 2 hours between the tests. The behavior is fairly repeatable. Results are updated on ExperimentationTissueMechanics page table (summary file name: oks00TR2-FMC-MCuX-03-01_02-repeatability.pdf).
 * Snehal will start cartilage repeatability tests for OKS001 from today. She plans to divide her time between completing testing for cartilage and troubleshooting meniscus and ligament testing. (18 out of planned 30 tests for each specimen are for cartilage)
 * Snehal also did one repeatability test for the cartilage tensile sample that was previously successfully tested for repeatability. The results show that the sample was stiffer than previous three tests (error<8%). Snehal thinks it might be due to freezing. Freezing-thawing the sample multiple times should therefore be minimized as much as possible. Results are updated on ExperimentationTissueMechanics page table (summary file name: oks00TR2-FMC-MCuX-02-01_04-repeatability.pdf).
 * Snehal will also get rectangular compression chamber and filter made for meniscus confined compression tests.

2. Segmentation progress.

 * None
  3. Manuscripts progress.

 * None

4. Other.
 * None		  1. Data manuscripts.
  * No progress.
 1. Tissue testing.
  * Snehal did additional repeatability tests for cartilage tensile test to increase confidence in the procedure and results. Two tests were done with 2 hours between the tests. The behavior is fairly repeatable. Results are updated on ExperimentationTissueMechanics page table (summary file name: oks00TR2-FMC-MCuX-03-01_02-repeatability.pdf).
  * Snehal will start cartilage repeatability tests for OKS001 from today. She plans to divide her time between completing testing for cartilage and troubleshooting meniscus and ligament testing. (18 out of planned 30 tests for each specimen are for cartilage)
  * Snehal also did one repeatability test for the cartilage tensile sample that was previously successfully tested for repeatability. The results show that the sample was stiffer than previous three tests (error<8%). Snehal thinks it might be due to freezing. Freezing-thawing the sample multiple times should therefore be minimized as much as possible. Results are updated on ExperimentationTissueMechanics page table (summary file name: oks00TR2-FMC-MCuX-02-01_04-repeatability.pdf).
  * Snehal will also get rectangular compression chamber and filter made for meniscus confined compression tests.
 1. Segmentation.
  * No progress.
 1. Other.
  * None noted.

Weekly Update in lieu of Recurring Meeting of Cleveland Clinic Core Team

Date: January 3, 2017

Provided by: Snehal Chokhandre

Ongoing Action Items:

  • Ahmet
    • Review drafts of data manuscripts for submission.
  • Snehal
    • Complete studies for tissue testing reproducibility.
    • Continue tissue testing of Open Knee(s) specimens.
  • All
    • Continue segmentation of Open Knee(s) specimens.

Notes:

  1. Data manuscripts.
    • No progress.
  2. Tissue testing.

    • Snehal did additional repeatability tests for cartilage tensile test to increase confidence in the procedure and results. Two tests were done with 2 hours between the tests. The behavior is fairly repeatable. Results are updated on ExperimentationTissueMechanics page table (summary file name: oks00TR2-FMC-MCuX-03-01_02-repeatability.pdf).

    • Snehal will start cartilage repeatability tests for OKS001 from today. She plans to divide her time between completing testing for cartilage and troubleshooting meniscus and ligament testing. (18 out of planned 30 tests for each specimen are for cartilage)

    • Snehal also did one repeatability test for the cartilage tensile sample that was previously successfully tested for repeatability. The results show that the sample was stiffer than previous three tests (error<8%). Snehal thinks it might be due to freezing. Freezing-thawing the sample multiple times should therefore be minimized as much as possible. Results are updated on ExperimentationTissueMechanics page table (summary file name: oks00TR2-FMC-MCuX-02-01_04-repeatability.pdf).

    • Snehal will also get rectangular compression chamber and filter made for meniscus confined compression tests.
  3. Segmentation.
    • No progress.
  4. Other.
    • None noted.

RecurringMeetings/2017-01-03-Update (last edited 2017-01-08 22:59:10 by aerdemir)