Weekly Update in lieu of Recurring Meeting of Cleveland Clinic Core Team

Date: February 28, 2017

Provided by: Snehal Chokhandre

Ongoing Action Items:


  1. Tissue testing.
    • Snehal conducted repeatability tests on a rubber sample for unconfined compression under lower strain rates. The strain rate for stress relaxation was 5%/s and preconditioning was done at 0.5 Hz. The behavior was not repeatable. Snehal ordered new rubber sheets as she was concerned the rubber sheet from which the sample was taken may have been damaged from previous use.
      • Snehal also dissected a 48 years old knee specimen and harvested all the required tissues. The tissues of interest appeared healthy on a visual inspection but the surrounding tissue (particularly muscles) did not. The expectation from the repeatability tests using samples from this specimen (especially cartilage) is that they will be similar to the 40 years old specimen's and be reasonably repeatable. Improved repeatability may indicate that degenerated tissue (as in case of the 78 yr old specimen) may be a cause of non repeatable behavior as it may not be recovering in between tests. The cartilage from this middle age specimen will be tested similarly to that from the 40 yr old specimen i.e. under unconfined compression, confined compression and tension in saline and without ramps before and after preconditioning.
      • Snehal also compared the applied displacements to assess whether any variations in those may be adding to the non repeatability of the data. However, the difference / error in applied displacements are within the resolution of 0.5 microns. Hence, an influence on the variations in repeatability is not expected. Similarly, the load cell readings are also repeatable over multiple calibrations.
      • Along with streamlining the current python scripts, Snehal will also start working on data fitting.
  2. Data manuscripts.
    • No progress.
  3. Segmentation.
    • No progress.
  4. Other.
    • None noted.

RecurringMeetings/2017-02-28-Update (last edited 2017-03-02 23:26:23 by aerdemir)