Weekly Update in lieu of Recurring Meeting of Cleveland Clinic Core Team
Date: March 14, 2017
Provided by: Snehal Chokhandre
Ongoing Action Items:
- Review drafts of data manuscripts for submission.
- Complete studies for tissue testing reproducibility.
- Continue tissue testing of Open Knee(s) specimens.
- Continue segmentation of Open Knee(s) specimens.
- Tissue testing.
Snehal completed four more tests for the previously tested rubber sample. Even though the first four tests were repeatable with ~5% error, the following four tests were not as repeatable, resulting in a >15% error. Snehal is still waiting for the rubber sheets she ordered so she can test samples with known properties.
- Snehal asked Martin from Biomomentum whether they use any rubber material for standardization / calibration and was informed that they only use calibrated springs.
- In the meantime, Snehal has started testing cartilage samples from the 48 years old specimen. She has started with unconfined compression without ramps before and after preconditioning. She is also only using saline. This was to keep the tests similar to the 40 yr old specimen. The hold times however were full 30 mins.
- Snehal is also working on a python script for strain measurement from tensile testing images.
- Data manuscripts.
- No progress.
- No progress.
- Snehal and Ahmet discussed the progression of model development and Ahmet suggested that Snehal should start with simple patellofemoral compression simulations. She will use the sets of geometries created by herself, Craig and Conner for oks001 and run the simulations to assess the effects of segmentation variations among users on the model predictions.
- Snehal and Ahmet also discussed automating the entire process from taking the unprocessed joint testing data, unprocessed tissue testing data and specimen geometries and meshing the geometries, assembling the model, fit appropriate material models and run the model for a given loading scenario.
- Snehal and Ahmet will meet periodically to discuss and continue simulation efforts (including building required tools for processing and automation).