Weekly Update in lieu of Recurring Meeting of Cleveland Clinic Core Team
Date: July 04, 2017
Provided by: Snehal Chokhandre
Ongoing Action Items:
- Review drafts of data manuscripts for submission.
- Complete studies for tissue testing reproducibility.
- Continue tissue testing of Open Knee(s) specimens.
- Continue segmentation of Open Knee(s) specimens.
- Tissue testing.
Snehal completed cartilage tensile test sets for both samples (48 yr old and 78 yr old). For the sample from the 48 yr old specimen, the error is <8% for the first 4 tests and ~12 % if last test is included. For the sample from the 78 yr old specimen the error for 5 tests conducted over 5 days is ~8 %. Both of these results are encouraging considering the sample size and test conditions over multiple days.
- One thing to note is that the cartilage tensile samples have to be uniform and ≤ 0.5 mm (thinner sample appear to behave better).
- Mach-1 software freezes randomly (not all the time) at higher sampling rate. Snehal has modified the specifications to use 10 Hz sampling rate only for stress relaxation ramps.
- Snehal received thicker filter (3 mm) for confined compression tests and will test samples from both the 48 and 78 yr old specimens next week (5 tests / sample over 5 days).
- Snehal is also working on a technical report for cartilage tissue testing performed so far. The goal is to make a decision on priority for tissue mechanical tests and image segmentation based on repeatability results by end of August.
- Snehal is also gathering information to compile standards for reporting tissue testing studies (could be published, but mostly for lab reference).
- Data manuscripts.
- No progress.
- Snehal has been going over segmentation attempts by other members in the group (including interns). It appears that all components for oks001 (multiple users), all bones (Diana), registration markers (Connor), patella cartilage (Robb), medial meniscus (Tara) are segmented so far. Snehal plans to go over all of these segmentation attempts and correct/ confirm the segmentation. This will save a huge amount of time instead of redoing segmentation for all these components. Snehal can therefore focus on all ligaments: 42, lateral meniscus: 7, femoral cartilage: 7 and tibia cartilage: 7, as well as geometry generation.
- None noted.