• RecurringMeetings
• 2016-02-02-1400

Recurring Meeting of Cleveland Clinic Core Team

Date: February 2, 2016

Time: 2:00 PM EST

Means: In person meeting

Attendees:

1. Ahmet Erdemir
2. Tammy Owings
3. Benjamin Landis
4. Robb Colbrunn
5. Tara Bonner
6. Callan Gillespie

Agenda:

1. Discuss immediate action items from past meetings.

   • http://wiki.simtk.org/multis/RecurringMeetings/2016-01-26

2. Update on new personnel.
3. Decide immediate action items for next meeting.
4. Other.

Immediate Action Items:

• Ahmet
  • Continue working on the design of ultrasound probe - force transducer attachment and the handle.
• Tammy
  • Recollect ultrasound imaging for probe comparisons.
  • Collect full ultrasound testing protocol, without force measurements, as a sample mock-up trial (next two weeks).
• Ben
  • Generate bone,fat,muscle,skin geometry as STL surfaces.
  • Start a wiki page on simple model in FEBio.
  • Start a repository area/folder to keep the simple model.
• Robb
  • Document ultrasound settings to display a pulse train on ultrasound images for synchronization.
  • Upload a sample ultrasound with a synchronization signal in the wiki.
  • Identify and acquire orientation/tilt sensors for quantification to integrate into ultrasound-force transducer system.
• Robb and Tara
  • Incorporate force measurement and synchronization in one data acquisition software.

Notes:

1. Discuss immediate action items from past meetings.
   • Ahmet has been working on the design of ultrasound probe - force transducer attachment. He iterated with the group some ideas on assembling the handle piece, i.e. once the piece is on the force transducer, the probe sleeve should be slid through it and locked in with the force transducer. He will most likely work with design engineers at the Department of Biomedical Engineering to implement the discussed design ideas.
   • Ahmet had a 3D printed prototype of the ultrasound probe 9L4 made. This can be used for usability testing and evaluate indentation tests.
   • Tammy met with the physicians and recognized that her understanding of the anatomy of musculoskeletal tissue layers, as imaged by ultrasound, match their appreciation of the anatomy. She will recollect some ultrasound images to finalize location specific probe selection. Ahmet also recommended that she conducts a mock-up test, including all anatomical and indentation measurements, to understand ease of the workflow and required time to do it.
   • Ben has worked with different contact settings in FEBio comparing performance of penalty contact with that of augmented Lagrangian formulation. With the latter, he had better success to obtain large deformations.
   • Ben was able to run simulations in FEBio under force control as long as the indenter and tissue are touching at the initial state. He had difficulties to implement a spring on the indenter. If done, that will help convergence issues when the indenter is in the air and force control of indentation is desired.
   • Ahmet asked Ben to imitate the anticipated workflow of modeling and simulation in the simple indentation model. This will require generation of STL surfaces for bone, fat, muscle, skin. In following, meshes of each of these structures will be generated and imported into FEBio to define the model and run simulations. Once completed, same workflow will be ported to SOFA for surgical simulations.
   • Robb placed photos of surgical tools and their handling on the wiki. He has completed the wiring to synchronize ultrasound imaging and force measurements. He looked at accelerometers as a way to measure the direction of gravitational acceleration for weight compensation of ultrasound probe. Ahmet recommended checking tilt sensors, e.g. mems based multi-sensors (gyroscope, accelerometer, etc.), as these may provide an off-the-shelf solution to measure ultrasound probe orientation.
2. Update on new personnel.

   • Ahmet mentioned that he has extended offers to two applicants, one as a senior research engineer and the other as a research associate. If accepted, the research engineer is anticipated to start in mid-March to work on cadaver experimentation and related data analysis and modeling. If accepted, the research associate is expected to start within a few months to work on scientific aspects of the modeling & simulation workflow. Other duties, for all personnel, may include analysis and scientific interpretation of in vivo data, e.g. ultrasound measurements of tissue thickness and indentation response.

3. Decide immediate action items for next meeting.
   • See Immediate Action Items above.
4. Other.
   • None noted.