• RecurringMeetings
• 2018-04-17

Recurring Meeting of Cleveland Clinic Core Team

Date: April 17, 2018

Time: 2:00 PM EST

Means: In person meeting

Attendees:

1. Ahmet Erdemir
2. Rici Neumann
3. Ariel Schwartz
4. Ben Landis
5. Tammy Owings

Agenda:

1. Manuscripts update.
2. Data dissemination update.
3. In vitro testing status.

4. Modeling & simulation status.

5. Review of immediate action items from past meeting.

   • https://simtk.org/plugins/moinmoin/multis/RecurringMeetings/2018-03-13

6. Decide immediate action items for next meeting.
7. Other.

Ongoing Action Items:

• Ben
  • Continue implementing full lumped tissue modeling and simulation workflow.
  • Follow up with FEBio folks about Mooney-Rivlin material implementation with in situ strain and Augmented Lagrangian not working with contact.
• Rici
  • Revise in vivo data manuscript for resubmission.
  • Continue development of manuscript on in vivo indentation stiffness.
  • Continue development of manuscript on tissue thickness measurement comparisons.
• Ahmet
  • Compile haptics libraries and SofaHAPI.
  • Review revised manuscript on instrumented ultrasound.
  • Review draft of model assembly manuscript.

Notes:

1. Manuscripts update.
   • Ahmet briefly reviewed the instrumented ultrasound paper and met with Tyler and discussed the response to reviewers and revisions (placing a focus on the use as a research tool). Tyler still needs to write up revisions.
   • Rici is working on revisions for the in vivo data paper and brought up indentation repeatability. Ahmet suggested using the thickness change as a metric for intra- and inter-person repeatability. The remaining revisions are minor. We plan to submit this back prior to re-submitting the instrumented ultrasound paper.
   • The extended abstract for IEEE EMBS 2018 on instrumentation of surgical tools was accepted and Tyler submitted final version. Ahmet talked with Tyler about the possibility of focusing on getting other data/analysis papers out rather than extending this work into a full length paper.
   • Work on in vivo surface stiffness manuscript will proceed after in vivo data paper has been revised.
   • Ahmet noted that the figures in Ben's model assembly paper looked good but he still needs to review the text.
2. Data dissemination update.
   • The Cleveland Clinic team still waits for the green light from Stanford University about the readiness of in vitro data management system for launch.
   • A new version should be ready this week which will implement the registration query feature requested by Rici.
   • Ahmet asked Rici to check in with Stanford on a bi-weekly basis at minimum with the hope of completing the in vitro data dissemination sometime in May.
3. In vitro testing status.
   • Tyler will be out-of-office until beginning of June. Surgical tool testing will start when he comes back. As of now, protocols are complete and software and hardware are operational. A full mock will be conducted when he returns back before testing starts.
   • Tissue characterization efforts will continue when Tyler returns back to office.

4. Modeling & simulation status.

   • Ahmet summarized Priority 1 for modeling and simulation. Initial focus was placed on the lumped model with inverse FEA implementation for material properties.
   • Ben had the first template model built also supporting inverse FEA. The model was calibrated to only the end point, so Ben will look into the comparison of model and experimental data during the indentation. Gravity compensation has not been used in these studies due to an issue with in situ strain feature when using Mooney-Rivlin material model (see below).
   • New version of Ben's model assembly scripts were uploaded. Abaqus scripts will be updated soon. Ahmet and Ben discussed the need to solidify the Salome version to be used and then updates can be made later to ensure compatibility with future versions of Salome. Snehal has tried to use Ben's scripts and has been having issues with new versions of Salome on her computer. Ahmet also suggested testing the scripts on different platforms in the future (i.e. Windows, MAC).
   • Ben has found some issues with the gravity compensation implementation w.r.t. the Mooney-Rivlin material definition in FEBio. A new version of FEBio is close to release which will hopefully fix this issue and they are additionally looking into a bug found in the in situ strain module. Ahmet suggested reaching out the the FEBio folks again to touch base about this issue.
   • Ahmet asked Ben if we should work on building other template models while the FEBio bugs get fixed. Ben did not like the idea of building all the template models because he is unsure if his current methods are going to be acceptable for the later portion of the simulation pipeline. He has some other ideas and tasks he would like to implement before building the additional template models.
   • Ben and Ahmet also discussed the potential use of Abaqus in place of FEBio. Ben has been working to run the models in Abaqus, which has better methods to handle contact. Ahmet noted that gravity compensation will, however, be more of a challenge.
   • A discussion about the determination of mesh density specifications was briefly discussed. Ariel will be writing up the specifications with a goal to reduce subjectivity when defining initial, coarse, and fine mesh densities. She talked about potentially using the element bounding box size as a metric to specify the mesh density.
5. Review of immediate action items from past meeting.
   • All action items were related to the agenda items; refer to discussions above.
6. Decide immediate action items for next meeting.
   • See Ongoing Action Items above.
7. Other.
   • Ahmet submitted the quarterly report.
   • Ahmet submitted ideas for future direction to US Army. The main theme is "configurable content", which focuses on developing methods to streamline the usability of the data and models that are currently being developed and disseminated.