• Subjects

Overview

This page provides experimentation notes related to the execution of Specifications/InVivoTesting. All raw and derivative data can be found on the dynamic data management site: https://multisbeta.stanford.edu/. In addition, a static version (frozen at the time of publication) of the data is provided (http://archive.simtk.org/multis/indexMULTIS.html).

Note: MULTIS013, MULTIS014, MULTIS044, MULTIS058, MULTIS060, MULTIS084, MULTIS087, and MULTIS101 are the closest to "military fit" among all the subjects.

Subjects 001-010

MULTIS001

• Force data should not be used for this subject due to problems with the load cell.
• Protocol Deviations:
  • Location #1 (Upper Arm - Anterior Proximal) was accidentally marked as not accepted. It was not possible to relabel it as accepted. The subject configuration file should show two rejected data sets for this location. The latter of the trials should have been accepted.
  • Location #55 (Lower Leg - Medial Proximal); it was difficult to target fibula. First trial may have not include the fibula boundary; therefore it was rejected. It was possible to visualize fibula in the second trial albeit barely.
  • In the data collection software, the trial counter, to indicate finalization of data collection, does not seem to be working.
• Thickness Analysis (Ultrasound)
  • Trial 045 (Lower Arm - Posterior Proximal): Missing the bone boundary (bright fascia is a false bone boundary).

MULTIS002

• Force data should not be used for this subject due to problems with the load cell.
• No major issues in regard to data collection.
• Thickness Analysis (Ultrasound)
  • Trial 012 (Lower Leg - Lateral Distal): Total thickness is higher than the other subjects and does not decrease by very much from the central and proximal locations, could be seeing the tibia instead of the fibula.
  • Trial 042 (Lower Leg - Posterior Proximal): Total thickness is smaller than expected, we are potentially seeing the fibula instead of the tibia.
  • Trial 045 (Lower Leg - Posterior Central): Total thickness is smaller than expected, we are potentially seeing the fibula instead of the tibia.
  • Trial 047 (Upper Leg - Anterior Proximal): Missing the bone boundary (bright fascia is a false bone boundary).
  • Trial 064 (Upper Leg - Medial Distal): Missing bone boundary (blood vessel appears as bone).

MULTIS003

• Used for load cell testing; no data reported.

MULTIS004

• Force data should not be used for this subject due to problems with the load cell.
• No Major issues in regard to data collection.
• Thickness Analysis (Ultrasound)
  • Trial 018 (Lower Leg - Lateral Distal): Total thickness larger than the other subjects, we are potentially capturing the tibia boundary instead of the fibula boundary.

MULTIS005

• Force data should not be used for this subject due to problems with the load cell.
• Protocol Deviations:
  • Data input error for lower leg distal circumference (original input was 217 cm, but it was later changed to 21.7 cm (2016-10-27), based on the assumption that the decimal point was not included).
  • Data input error for knee landmark to proximal circumference (original input was 76 cm, but it was later changed to 7.6 cm (2017-08-31), based on the assumption that the decimal point was not included).
  • Trial 040 (Upper Arm - Posterior Central); labeled as an indentation trial, but indentation was not performed. No indentation trial for this location.
• Thickness Analysis (Ultrasound)
  • Trial 027 (Lower Arm - Medial Distal): Difficult to distinguish where the muscle fascia is located.
  • Trial 032 (Lower Arm - Posterior Central): Total thickness is smaller than the distal location, could be capturing a fascia boundary instead of bone boundary.
  • Trial 047 (Lower Leg - Posterior Proximal): Total thickness is smaller than expected, we are potentially seeing the fibula instead of the tibia.
  • Trial 048 (Lower Leg - Posterior Central): Total thickness is smaller than expected, we are potentially seeing the fibula instead of the tibia.

MULTIS006

• Protocol Deviations:
  • Trial 26 and 29 were mislabeled during data collection
    • Trial 26 should be LA_PD (distal)
    • Trial 29 should be LA_PP (proximal)
• Thickness Analysis (Ultrasound)
  • Trial 30 (Lower Leg - Posterior Distal): Missing the bone boundary.

MULTIS007

• Protocol Deviations:
  • Trial 35 and 41 were mislabeled during data collection
    • Trial 35 should be LA_PD (distal)
    • Trial 41 should be LA_PP (proximal)
  • Trial 036 had two ultrasound images associated with it. The first one with .36 in the name was incorrect. The multisbeta.stanford.edu repository was updated on October 13th, 2020.

MULTIS008

• No major issues in regard to data collection.
• This subject used for repeatability
  • Inclusion.xml - Analyzer 1, analysis 1
  • Inclusion_2.xml - Analyzer 1, analysis 2
  • Inclusion_3.xml - Analyzer 2, analysis 1

MULTIS009

• Protocol Deviations:
  • Trial 64 (Lower Leg Medial Proximal): Unable to locate the fibula during the data collection
• Thickness Analysis (Ultrasound)
  • Trial 64 (Lower Leg Medial Proximal): Missing bone boundary.

MULTIS010

• Protocol Deviations:
  • Trial 63 (Upper Leg Medial Proximal): Unable to locate the femur during the data collection
  • Trial 64 (Upper Leg Medial Central): Unable to locate the femur during the data collection
• Thickness Analysis (Ultrasound)
  • Trial 63 (Upper Leg Medial Proximal): Missing bone boundary.
  • Trial 64 (Upper Leg Medial Central): Missing bone boundary.
  • Trial 69 (Lower Leg Medial Proximal): Missing bone boundary.

Subjects 011-020

MULTIS011

• Protocol Deviations:
  • Trial 11 and 14 were mislabeled during data collection
    • Trial 11 should be LA_AD (distal)
    • Trial 14 should be LA_AP (proximal)
  • Trial 15 and 17 were mislabeled during data collection
    • Trial 15 should be LA_LD (distal)
    • Trial 17 should be LA_LP (proximal)
  • Trial 18 and 21 were mislabeled during data collection
    • Trial 18 should be LA_MD (distal)
    • Trial 21 should be LA_MP (proximal)
  • Trial 29 and 34 were mislabeled during data collection
    • Trial 29 should be LA_PD (distal)
    • Trial 34 should be LA_PP (proximal)

MULTIS012

• No major issues in regard to data collection.

MULTIS013

• Protocol Deviations:
  • Data input error for elbow landmark to distal circumference (original input was 13.5 cm, but it was later changed to 23.5 cm (2017-08-31), based on the assumption that the a '1' was typed instead of a '2' during data entry).
  • Thickness Analysis (Ultrasound):
    • Trial 065 (Lower Leg Medial Proximal): Missing bone and going to other side of skin? Total thickness seems too large. Removed muscle/bone interface marker (2017-09-28).
    • Trial 068 (Lower Leg Medial Central): Seems too large, missing bone? Removed muscle/bone interface marker (2017-09-28).

MULTIS014

• No major issues in regard to data collection.

MULTIS015

• Protocol Deviations:
  • Trial 038 and 039 (Lower Leg Posterior Central): Unable to locate the fibula during data collection (both anatomical and indentation).
  • Trial 054 (Upper Leg Medial Proximal): Unable to locate the femur during data collection.
  • Trial 060 (Lower Leg Medial Proximal): Unable to locate the fibula during data collection.
  • Trial 26 and 29 were mislabeled during data collection (?)
    • Trial 26 should be LA_PD (distal)
    • Trial 29 should be LA_PP (proximal)
• Thickness Analysis (Ultrasound)
  • Trial 009 (Upper Arm Medial Proximal): Difficult to distinguish fat/muscle boundary
  • Trial 010 (Upper Arm Medial Central): Difficult to distinguish fat/muscle boundary
  • Trial 011 (Upper Arm Medial Distal): Difficult to distinguish fat/muscle boundary
  • Trial 012 (Lower Arm Anterior Proximal): Missing bone. Removed muscle/bone interface marker (2017-09-28).
  • Trial 038 and 039 (Lower Leg Posterior Central): Missing bone boundary in anatomical and indentation trials.
  • Trial 054 (Upper Leg Medial Proximal): Missing bone boundary.
  • Trial 060 (Lower Leg Medial Proximal): Missing bone boundary.

MULTIS016

• Protocol Deviations:
  • Trial 067 (Lower Leg Medial Proximal): Unable to locate the fibula during data collection.
  • Trial 060 (Upper Leg Medial Central): Does not have associated ultrasound image since there are no RWaves present.
• Thickness Analysis (Ultrasound)
  • Trial 067 (Lower Leg Medial Proximal): Missing bone boundary.
  • Trial 060 (Upper Leg Medial Central): Not analyzed.

MULTIS017

• No major issues in regard to data collection.
• Thickness Analysis (Ultrasound):
  • Trial 034 (Lower Leg Posterior Distal): Seems too small, missing bone? Removed muscle/bone interface marker (2017-09-28).

MULTIS018

• Protocol Deviations:
  • Trial 060 (Lower Leg Medial Proximal): Unable to locate the fibula during data collection.
• Thickness Analysis (Ultrasound)
  • Trial 057 (Lower Leg Anterior Proximal): Missing bone. Removed muscle/bone interface marker (2017-09-28).
  • Trial 058, 059 (Lower Leg Anterior Central): Missing bone, or bone is in the middle of the image (difficult to distinguish boundary). Removed muscle/bone interface marker (2017-09-28).
  • Trial 060 (Lower Leg Medial Proximal): Missing bone boundary.

MULTIS019

• No major issues in regard to data collection.

MULTIS020

• Protocol Deviations:
  • Trial 031 (Upper Leg Posterior Proximal): Unable to locate the femur during data collection.
  • Trial 032 and 033 (Upper Leg Posterior Central): Both anatomical and indentation unable to locate the femur during data collection.
  • Trial 053 (Upper Leg Medial Proximal): Unable to locate the femur during data collection.
  • Trial 062 (Lower Leg Medial Proximal): Unable to locate the fibula during data collection.
• Thickness Analysis (Ultrasound)
  • Trial 011 (Lower Arm Anterior Proximal): Missing bone. Removed muscle/bone interface marker (2017-09-28).
  • Trial 026 (Lower Arm Posterior Proximal): Missing bone. Removed muscle/bone interface marker (2017-09-28).
  • Trial 027/28 (Lower Arm Posterior Central): Missing bone. Removed muscle/bone interface marker (2017-09-28).
  • Trial 031 (Upper Leg Posterior Proximal): Missing bone boundary.
  • Trial 032 and 033 (Upper Leg Posterior Central): Missing bone boundary.
  • Trial 053 (Upper Leg Medial Proximal): Missing bone boundary.
  • Trial 062 (Lower Leg Medial Proximal): Missing bone boundary.

Subjects 021-030

MULTIS021

• No major issues in regard to data collection.

MULTIS022

• No major issues in regard to data collection.

MULTIS023

• No major issues in regard to data collection.
• This subject used for repeatability
  • Inclusion.xml - Analyzer 1, analysis 1
  • Inclusion_2.xml - Analyzer 1, analysis 2
  • Inclusion_3.xml - Analyzer 2, analysis 1

MULTIS024

• Protocol Deviations:
  • Trial 071 (Lower Leg Medial Proximal): Unable to locate the fibula during data collection.
  • Trial 073 (Lower Leg Medial Central): Unable to locate the fibula during data collection.
• Thickness Analysis (Ultrasound)
  • Trial 071 (Lower Leg Medial Proximal): Missing bone boundary.
  • Trial 073 (Lower Leg Medial Central): Missing bone boundary.

MULTIS025

• No major issues in regard to data collection.

MULTIS026

• Protocol Deviations:
  • Trial 062 (Lower Leg Medial Proximal): Unable to locate the fibula during data collection.
• Thickness Analysis (Ultrasound)
  • Trial 062 (Lower Leg Medial Proximal): Missing bone boundary.

MULTIS027

• Protocol Deviations:
  • Trial 061 (Lower Leg Medial Proximal): Unable to locate the fibula during data collection.
  • Trial 064 (Lower Leg Medial Central): Unable to locate the fibula during data collection.
• Thickness Analysis (Ultrasound)
  • Trial 061 (Lower Leg Medial Proximal): Missing bone boundary.
  • Trial 064 (Lower Leg Medial Central): Missing bone boundary.

MULTIS028

• Protocol Deviations:
  • Trial 061 (Lower Leg Medial Proximal): Unable to locate the fibula during data collection.
• Thickness Analysis (Ultrasound)
  • Trial 061 (Lower Leg Medial Proximal): Missing bone boundary.

MUTLIS029

• Protocol Deviations:
  • Trial 059 (Lower Leg Medial Proximal): Unable to locate the fibula during data collection.
  • Trial 061 (Lower Leg Medial Central): Unable to locate the fibula during data collection.
• Thickness Analysis (Ultrasound)
  • Trial 059 (Lower Leg Medial Proximal): Missing bone boundary.
  • Trial 061 (Lower Leg Medial Central): Missing bone boundary.

MULTIS030

• Protocol Deviations:
  • Trial 057 (Lower Leg Medial Proximal): Unable to locate the fibula during data collection.
• Thickness Analysis (Ultrasound)
  • Trial 057 (Lower Leg Medial Proximal): Missing bone boundary.

Subjects 031-040

MUTLIS031

• No major issues in regard to data collection.
• Thickness Analysis (Ultrasound)
  • Trial 001 (Upper Arm Anterior Proximal): Total thickness seems high for a subject that has one of the smallest circumferences at this location, however the central and distal images are similar to the typical ultrasound image at this location.

MULTIS032

• Protocol Deviations:
  • Trial 067 (Lower Leg Medial Proximal): Unable to locate the fibula during data collection. Bone that is visible is tibia.
• Thickness Analysis (Ultrasound)
  • Trial 067 (Lower Leg Medial Proximal): Missing bone boundary.

MULTIS033

• Protocol Deviations:
  • Trial 060 (Lower Leg Medial Proximal): Unable to locate the fibula during data collection. Bone that is visitble is tibia.
• Thickness Analysis (Ultrasound)
  • Trial 060 (Lower Leg Medial Proximal): Missing bone boundary.

MULTIS034

• Protocol Deviations:
  • Trial 058 (Lower Leg Medial Proximal): Unable to locate the fibula during data collection.
  • Trial 059 (Lower Leg Medial Central): Unable to locate the fibula during data collection.
• Thickness Analysis (Ultrasound)
  • Trial 058 (Lower Leg Medial Proximal):Missing bone boundary.
  • Trial 059 (Lower Leg Medial Central): Missing bone boundary.

MULTIS035

• Protocol Deviations:
  • Trial 057 (Lower Leg Medial Proximal): Unable to locate the fibula during data collection.
• Thickness Analysis (Ultrasound)
  • Trial 057 (Lower Leg Medial Proximal): Missing bone boundary.

MUTLIS036

• No major issues in regard to data collection.

MULTIS037

• Protocol Deviations:
  • Trial 063 (Lower Leg Medial Proximal): Unable to locate the fibula during data collection.
  • Trial 064 (Lower Leg Medial Central): Unable to locate the fibula during data collection.
• Thickness Analysis (Ultrasound)
  • Trial 063 (Lower Leg Medial Proximal): Missing bone boundary.
  • Trial 064 (Lower Leg Medial Central): Missing bone boundary.

MULTIS038

• Protocol Deviations:
  • Trial 062 (Lower Leg Medial Proximal): Unable to locate the fibula during data collection.
  • Trial 063 (Lower Leg Medial Central): Unable to locate the fibula during data collection.
• Thickness Analysis (Ultrasound)
  • Trial 062 (Lower Leg Medial Proximal): Missing bone boundary.
  • Trial 063 (Lower Leg Medial Central): Missing bone boundary.

MULTIS039

• Protocol Deviations:
  • Trial 061 (Lower Leg Medial Proximal): Unable to locate the fibula during data collection.
  • Trial 062 (Lower Leg Medial Central): Unable to locate the fibula during data collection.
• Thickness Analysis (Ultrasound)
  • Trial 061 (Lower Leg Medial Proximal): Missing bone boundary.
  • Trial 062 (Lower Leg Medial Central): Missing bone boundary.

MULTIS040

• Protocol Deviations:
  • Trial 038 (Upper Leg Posterior Proximal): Unable to locate the femur during data collection.
  • Trial 063 (Lower Leg Medial Proximal): Unable to locate the fibula during data collection.
  • Trial 064 (Lower Leg Medial Central): Unable to locate the fibula during data collection.
• Thickness Analysis (Ultrasound)
  • Trial 056 (Lower Arm Lateral Central): Larger than expected and ultrasound topology looks different than majority of other subjects. Use caution with results.
  • Trial 038 (Upper Leg Posterior Proximal): Missing bone boundary.
  • Trial 063 (Lower Leg Medial Proximal): Missing bone boundary.
  • Trial 064 (Lower Leg Medial Central): Missing bone boundary.

Subjects 041-050

MULTIS041

• Protocol Deviations:
  • Trial 057 (Lower Leg Medial Proximal): Unable to locate the fibula during data collection.
  • Trial 058 (Lower Leg Medial Central): Unable to locate the fibula during data collection.
• Thickness Analysis (Ultrasound)
  • Trial 057 (Lower Leg Medial Proximal): Missing bone boundary.
  • Trial 058 (Lower Leg Medial Central): Missing bone boundary.

MULTIS042

• No major issues in regard to data collection.
• This subject used for repeatability
  • Inclusion.xml - Analyzer 1, analysis 1
  • Inclusion_2.xml - Analyzer 1, analysis 2
  • Inclusion_3.xml - Analyzer 2, analysis 1

MULTIS043

• Protocol Deviations:
  • Trial 059 (Lower Leg Medial Proximal): Unable to locate the fibula during data collection.
  • Trial 060 (Lower Leg Medial Central): Unable to locate the fibula during data collection.
• Thickness Analysis (Ultrasound)
  • Trial 059 (Lower Leg Medial Proximal): Missing bone boundary.
  • Trial 060 (Lower Leg Medial Central): Missing bone boundary.

MULTIS044

• Protocol Deviations:
  • Trial 059 (Lower Leg Medial Proximal): Unable to locate the fibula during data collection.
  • Trial 060 (Lower Leg Medial Central): Unable to locate the fibula during data collection.
• Thickness Analysis (Ultrasound)
  • Trial 059 (Lower Leg Medial Proximal): Missing bone boundary.
  • Trial 060 (Lower Leg Medial Central): Missing bone boundary.

MULTIS045

• Protocol Deviations:
  • Trial 061 (Lower Leg Medial Proximal): Unable to locate the fibula during data collection.
  • Trial 062 (Lower Leg Medial Central): Unable to locate the fibula during data collection.
  • Lower Leg Medial Distal ???
• Thickness Analysis (Ultrasound)
  • Trial 061 (Lower Leg Medial Proximal): Missing bone boundary.
  • Trial 062 (Lower Leg Medial Central): Missing bone boundary.

MULTIS046

• Protocol Deviations:
  • Trial 030 (Upper Leg Posterior Proximal): Unable to locate the femur during data collection.
  • Trial 031 and 032 (Upper Leg Posterior Central): Unable to locate the femur during data collection (both anatomical and indentation trials).
  • Trial 058 (Lower Leg Medial Proximal): Unable to locate the fibula during data collection.
  • Trial 059 (Lower Leg Medial Central): Unable to locate the fibula during data collection.
• Thickness Analysis (Ultrasound)
  • Trial 030 (Upper Leg Posterior Proximal): Missing bone boundary.
  • Trial 031 and 032 (Upper Leg Posterior Central): Missing bone boundary (both anatomical and indentation trials).
  • Trial 058 (Lower Leg Medial Proximal): Missing bone boundary.
  • Trial 059 (Lower Leg Medial Central): Missing bone boundary.

MULTIS047

• Protocol Deviations:
  • Trial 063 (Lower Leg Medial Proximal): Unable to locate the fibula during data collection.
  • Trial 064 (Lower Leg Medial Central): Unable to locate the fibula during data collection.
• Thickness Analysis (Ultrasound)
  • Trial 063 (Lower Leg Medial Proximal): Missing bone boundary.
  • Trial 064 (Lower Leg Medial Central): Missing bone boundary.

MULTIS048

• Protocol Deviations:
  • Trial 057 (Lower Leg Medial Proximal): Unable to locate the fibula during data collection.
• Thickness Analysis (Ultrasound)
  • Trial 057 (Lower Leg Medial Proximal): Missing bone boundary.

MULTIS049

• No major issues in regard to data collection.

MULTIS050

• Protocol Deviations:
  • Trial 047 (Upper Leg Lateral Proximal): Unable to locate the femur during data collection.
  • Trial 050 (Upper Leg Medial Proximal): Unable to locate the femur during data collection.
  • Upper leg lateral - not sure if the bone was reached in any lateral images.
  • Trial 058 (Lower Leg Medial Proximal): Unable to locate the fibula during data collection.
  • Trial 059 (Lower Leg Medial Central): Unable to locate the fibula during data collection.
  • Upper arm anterior, medial, lateral and all of the lower arm, and lateral lower leg and anterior distal lower leg done with 14L5 however the computer recorded it as 9L4 probe.
• Thickness Analysis (Ultrasound)
  • Trial 047 (Upper Leg Lateral Proximal): Missing bone boundary.
  • Trial 050 (Upper Leg Medial Proximal): Missing bone boundary.
  • Trial 058 (Lower Leg Medial Proximal): Missing bone boundary.
  • Trial 059 (Lower Leg Medial Central): Missing bone boundary.

Subjects 051-060

MULTIS051

• Protocol Deviations:
  • Trial 058 (Lower Leg Medial Proximal): Unable to locate the fibula during data collection.
  • Trial 059 (Lower Leg Medial Central): Unable to locate the fibula during data collection.
• Thickness Analysis (Ultrasound)
  • Trial 058 (Lower Leg Medial Proximal): Missing bone boundary.
  • Trial 059 (Lower Leg Medial Central): Missing bone boundary.

MULTIS052

• Protocol Deviations:
  • Trial 058 (Lower Leg Medial Proximal): Unable to locate the fibula during data collection.
  • Trial 059 (Lower Leg Medial Central): Unable to locate the fibula during data collection.
• Thickness Analysis (Ultrasound)
  • Trial 058 (Lower Leg Medial Proximal): Missing bone boundary.
  • Trial 059 (Lower Leg Medial Central): Missing bone boundary.

MULTIS053

• Protocol Deviations:
  • Trial 059 (Lower Leg Medial Proximal): Unable to locate the fibula during data collection.
  • Trial 060 (Lower Leg Medial Central): Unable to locate the fibula during data collection.
• Thickness Analysis (Ultrasound)
  • Trial 059 (Lower Leg Medial Proximal): Missing bone boundary.
  • Trial 060 (Lower Leg Medial Central): Missing bone boundary.

MULTIS054

• No major issues in regard to data collection.

MULTIS055

• Protocol Deviations:
  • Trial 032 (Upper Leg Posterior Proximal): Unable to locate the femur during data collection.
  • Trial 057 (Lower Leg Medial Proximal): Unable to locate the fibula during data collection.
  • Trial 058 (Lower Leg Medial Central): Unable to locate the fibula during data collection.
• Thickness Analysis (Ultrasound)
  • Trial 032 (Upper Leg Posterior Proximal): Missing bone boundary.
  • Trial 057 (Lower Leg Medial Proximal): Missing bone boundary.
  • Trial 058 (Lower Leg Medial Central): Missing bone boundary.

MULTIS056

• Protocol Deviations:
  • Trial 059 (Lower Leg Medial Proximal): Unable to locate the fibula during data collection.
• Thickness Analysis (Ultrasound)
  • Trial 056 (Lower Leg Anterior Proximal): Missing bone. Removed muscle/bone interface marker (2017-09-28).
  • Trial 059 (Lower Leg Medial Proximal): Missing bone boundary.

MULTIS057

• Protocol Deviations:
  • Trial 062 (Lower Leg Medial Proximal): Unable to locate the fibula during data collection.
• Thickness Analysis (Ultrasound)
  • Trial 035 (Lower Leg Posterior Distal): Missing bone boundary. Removed muscle/bone interface marker (2017-09-28).
  • Trial 062 (Lower Leg Medial Proximal): Missing bone boundary.

MULTIS058

• Protocol Deviations:
  • Trial 062 (Lower Leg Medial Proximal): Unable to locate the fibula during data collection.
  • Trial 063 (Lower Leg Medial Central): Unable to locate the fibula during data collection.
• Thickness Analysis (Ultrasound)
  • Trial 062 (Lower Leg Medial Proximal): Missing bone boundary.
  • Trial 063 (Lower Leg Medial Central): Missing bone boundary.

MULTIS059

• Protocol Deviations:
  • Data input error for knee landmark to central circumference (original input was 212 cm, but it was later changed to 21.2 cm (2017-08-31), based on the assumption that the decimal point was not included).
  • Trial 065 (Lower Leg Medial Proximal): Unable to locate the fibula during data collection.
• Thickness Analysis (Ultrasound)
  • Trial 065 (Lower Leg Medial Proximal): Missing bone boundary.

MULTIS060

• No major issues in regard to data collection.
• Thickness Analysis (Ultrasound)
  • Trial 030 (Lower Leg Posterior Distal): Missing bone boundary. Removed muscle/bone interface marker (2017-09-28).

Subjects 061-070

MULTIS061

• No major issues in regard to data collection.
• This subject used for repeatability
  • Inclusion.xml - Analyzer 1, analysis 1
  • Inclusion_2.xml - Analyzer 1, analysis 2
  • Inclusion_3.xml - Analyzer 2, analysis 1

MULTIS062

• Protocol Deviations:
  • Trial 062 (Lower Leg Medial Proximal): Unable to locate the fibula during data collection.
• Thickness Analysis (Ultrasound)
  • Trial 062 (Lower Leg Medial Proximal): Missing bone boundary.

MULTIS063

• No major issues in regard to data collection, but for Trial 059 (Lower Leg Medial Central): The location of the fibula is faint, but is noticeable on the lower right side of screen.

MULTIS064

• Protocol Deviations:
  • Trial 059 (Lower Leg Medial Proximal): Unable to locate the fibula during data collection.
  • Trial 060 (Lower Leg Medial Central): Unable to locate the fibula during data collection.
• Thickness Analysis (Ultrasound)
  • Trial 059 (Lower Leg Medial Proximal): Missing bone boundary.
  • Trial 060 (Lower Leg Medial Central): Missing bone boundary.

MULTIS065

• Protocol Deviations:
  • Trial 062 (Lower Leg Medial Proximal): Unable to locate the fibula during data collection.
  • Trial 063 (Lower Leg Medial Central): Unable to locate the fibula during data collection.
  • Upper Leg Posterior Proximal - Very faint (one spot shows bone)
• Thickness Analysis (Ultrasound)
  • Trial 062 (Lower Leg Medial Proximal): Missing bone boundary.
  • Trial 063 (Lower Leg Medial Central): Missing bone boundary.

MULTIS066

• No major issues in regard to data collection.

MULTIS067

• Protocol Deviations:
  • Trial 065 (Lower Leg Medial Proximal): Unable to locate the fibula during data collection.
  • Trial 066 (Lower Leg Medial Central): Unable to locate the fibula during data collection.
• Thickness Analysis (Ultrasound)
  • Trial 030 (Lower Leg Posterior Distal): Missing bone boundary. Removed muscle/bone interface marker (2017-09-28).
  • Trial 065 (Lower Leg Medial Proximal): Missing bone boundary.
  • Trial 066 (Lower Leg Medial Central): Missing bone boundary.

MULTIS068

• Protocol Deviations:
  • Trial 059 (Lower Leg Medial Proximal): Unable to locate the fibula during data collection.
  • Trial 060 (Lower Leg Medial Central): Unable to locate the fibula during data collection.
• Thickness Analysis (Ultrasound)
  • Trial 059 (Lower Leg Medial Proximal): Missing bone boundary.
  • Trial 060 (Lower Leg Medial Central): Missing bone boundary.

MULTIS069

• Protocol Deviations:
  • Trial 057 (Lower Leg Medial Central): Difficult to find bone, unsure if the captured image shows a valid bone boundary.

MULTIS070

• Protocol Deviations:
  • Trial 030 (Upper Leg Posterior Proximal): Difficult to locate the femur. May not have the correct bone boundary.
  • Trial 057 (Lower Leg Medial Proximal): Unable to locate the fibula during data collection.
  • Trial 058 (Lower Leg Medial Central): Unable to locate the fibula during data collection.
• Thickness Analysis (Ultrasound)
  • Trial 030 (Upper Leg Posterior Proximal): Missing bone boundary.
  • Trial 057 (Lower Leg Medial Proximal): Missing bone boundary.
  • Trial 058 (Lower Leg Medial Central): Missing bone boundary.

Subjects 071-080

MULTIS071

• Protocol Deviations:
  • Data measurement error for elbow landmark to distal circumference (original input was 22.8 cm, but it was later changed to 21.8 cm (2017-08-31), based on the assumption that the measuring tape was misread - length to distal circumference was longer than total segment length, by looking at the distance between the central and proximal circumferences, the distance to the distal circumference should have been around 21.8 cm).
  • Trial 062 (Lower Leg Medial Proximal): Unable to locate the fibula during data collection.
  • Trial 064 (Lower Leg Medial Central): Unable to locate the fibula during data collection.
• Thickness Analysis (Ultrasound)
  • Trial 062 (Lower Leg Medial Proximal): Missing bone boundary.
  • Trial 064 (Lower Leg Medial Central): Missing bone boundary.

MULTIS072

• Protocol Deviations:
  • Trial 033 (Upper Leg Posterior Proximal): Unable to locate the femur during data collection.
  • Trial 053 (Upper Leg Lateral Proximal): Unable to locate the femur during data collection.
  • Trial 063 (Lower Leg Medial Proximal): Unable to locate the fibula during data collection.
    • Trial 064 (Lower Leg Medial Central): Unable to locate the fibula during data collection.
• Thickness Analysis (Ultrasound)
  • Trial 033 (Upper Leg Posterior Proximal): Missing bone boundary.
  • Trial 053 (Upper Leg Lateral Proximal): Missing bone boundary.
  • Trial 063 (Lower Leg Medial Proximal): Missing bone boundary.
  • Trial 064 (Lower Leg Medial Central): Missing bone boundary.

MULTIS073

• No major issues in regard to data collection.

MULTIS074

• No major issues in regard to data collection.

MULTIS075

• Protocol Deviations:
  • Trial 060 (Lower Leg Medial Proximal): Unable to locate the fibula during data collection.
• Thickness Analysis (Ultrasound)
  • Trial 060 (Lower Leg Medial Proximal): Missing bone boundary.

MULTIS076

• Protocol Deviations:
  • Trial 030 (Upper Leg Posterior Proximal): Unable to locate the femur during data collection.
  • Trial 054 (Upper Leg Lateral Proximal): Unable to locate the femur during data collection.
  • Trial 057 (Upper Leg Medial Proximal): Unable to locate the femur during data collection.
  • Trial 063 (Lower Leg Medial Proximal): Unable to locate the fibula during data collection.
  • Trial 064 (Lower Leg Medial Central): Unable to locate the fibula during data collection.
• Thickness Analysis (Ultrasound)
  • Trial 030 (Upper Leg Posterior Proximal): Missing bone boundary.
  • Trial 054 (Upper Leg Lateral Proximal): Missing bone boundary.
  • Trial 057 (Upper Leg Medial Proximal): Missing bone boundary.
  • Trial 063 (Lower Leg Medial Proximal): Missing bone boundary.
  • Trial 064 (Lower Leg Medial Central): Missing bone boundary.

MULTIS077

• Protocol Deviations:
  • Trial 062 (Lower Leg Medial Proximal): Unable to locate the fibula during data collection.
  • Trial 063 (Lower Leg Medial Central): Unable to locate the fibula during data collection.
• Thickness Analysis (Ultrasound)
  • Trial 032 (Upper Leg Posterior Proximal): Missing bone boundary. Removed muscle/bone interface marker (2017-09-28).
  • Trial 062 (Lower Leg Medial Proximal): Missing bone boundary.
  • Trial 063 (Lower Leg Medial Central): Missing bone boundary.

MULTIS078

• No major issues in regard to data collection.

MULTIS079

• Protocol Deviations:
  • Trial 061 (Lower Leg Medial Proximal): Unable to locate the fibula during data collection.
  • Trial 062 (Lower Leg Medial Central): Unable to locate the fibula during data collection.
• Thickness Analysis (Ultrasound)
  • Trial 061 (Lower Leg Medial Proximal): Missing bone boundary.
  • Trial 062 (Lower Leg Medial Central): Missing bone boundary.

MULTIS080

• Protocol Deviations:
  • Trial 028 (Upper Leg Posterior Proximal): Unable to locate the femur during data collection.
  • Trial 029,030 (Upper Leg Posterior Central): Unable to locate the femur during data collection.
  • Trial 031 (Upper Leg Posterior Distal): Unable to locate the femur during data collection.
  • Trial 033 (Lower Leg Posterior Proximal): Unable to locate the humerus during data collection.
  • Trial 035,036 (Lower Leg Posterior Central): Unable to locate the humerus during data collection.
  • Trial 064 (Lower Leg Medial Proximal): Unable to locate the fibula during data collection.
  • Trial 065 (Lower Leg Medial Central): Unable to locate the fibula during data collection.
• Thickness Analysis (Ultrasound)
  • Trial 028 (Upper Leg Posterior Proximal): Missing bone boundary.
  • Trial 029,030 (Upper Leg Posterior Central): Missing bone boundary.
  • Trial 031 (Upper Leg Posterior Distal): Missing bone boundary.
  • Trial 033 (Lower Leg Posterior Proximal): Missing bone boundary.
  • Trial 035,036 (Lower Leg Posterior Central): Missing bone boundary.
  • Trial 047 (Lower Leg Lateral Central): Missing bone boundary. Removed muscle/bone interface marker (2017-09-28).
  • Trial 064 (Lower Leg Medial Proximal): Missing bone boundary.
  • Trial 065 (Lower Leg Medial Central): Missing bone boundary.

Subjects 081-090

MULTIS081

• Protocol Deviations:
  • Trial 064 (Lower Leg Medial Central): Unsure if located the fibula during data collection.
• Thickness Analysis (Ultrasound)
  • Trial 064 (Lower Leg Medial Central): Missing bone boundary.

MULTIS082

• Protocol Deviations:
  • Trial 057 (Lower Leg Medial Proximal): Unable to locate the fibula during data collection.
  • Trial 058 (Lower Leg Medial Central): Unable to locate the fibula during data collection.
• Thickness Analysis (Ultrasound)
  • Trial 057 (Lower Leg Medial Proximal): Missing bone boundary.
  • Trial 058 (Lower Leg Medial Central): Missing bone boundary.

MULTIS083

• Protocol Deviations:
  • Trial 058 (Lower Leg Medial Proximal): Unable to locate the fibula during data collection.
  • Trial 059 (Lower Leg Medial Central): Unable to locate the fibula during data collection.
• Thickness Analysis (Ultrasound)
  • Trial 058 (Lower Leg Medial Proximal): Missing bone boundary.
  • Trial 059 (Lower Leg Medial Central): Missing bone boundary.

MULTIS084

• Protocol Deviations:
  • Trial 055 (Lower Leg Medial Proximal): Unable to locate the fibula during data collection.
• Thickness Analysis (Ultrasound)
  • Trial 058 (Lower Leg Medial Proximal): Missing bone boundary.

MULTIS085

• Protocol Deviations:
  • Trial 030 (Upper Leg Posterior Proximal): Unable to locate the femur during data collection.
  • Trial 031 and 032 (Upper Leg Posterior Proximal): Unsure about femur boundary.
  • Trial 061 (Lower Leg Medial Proximal): Unable to locate the fibula during data collection.
  • Trial 062 (Lower Leg Medial Central): Unable to locate the fibula during data collection.
• Thickness Analysis (Ultrasound)
  • Trial 030 (Upper Leg Posterior Proximal): Missing bone boundary.
  • Trial 031 and 032 (Upper Leg Posterior Central): Missing bone boundary.
  • Trial 061 (Lower Leg Medial Proximal): Missing bone boundary.
  • Trial 062 (Lower Leg Medial Central): Missing bone boundary.

MULTIS086

• No major issues in regard to data collection.

MULTIS087

• No major issues in regard to data collection.
• This subject used for repeatability
  • Inclusion.xml - Analyzer 1, analysis 1
  • Inclusion_2.xml - Analyzer 1, analysis 2
  • Inclusion_3.xml - Analyzer 2, analysis 1

MULTIS088

• Protocol Deviations:
  • Trial 053 (Upper Leg Medial Proximal): Unable to locate the femur during data collection.
  • Trial 067 (Lower Leg Medial Proximal): Unable to locate the fibula during data collection.
  • Trial 068 (Lower Leg Medial Central): Unable to locate the fibula during data collection.
• Thickness Analysis (Ultrasound)
  • Trial 053 (Upper Leg Medial Proximal): Missing bone boundary.
  • Trial 067 (Lower Leg Medial Proximal): Missing bone boundary.
  • Trial 068 (Lower Leg Medial Central): Missing bone boundary.

MULTIS089

• Protocol Deviations:
  • Data input error for shoulder landmark to proximal circumference (original input was 27.6 cm, but it was later changed to 7.6 cm (2017-08-31), based on the assumption that an "2" was mis-typed - length to proximal circumference was longer than total segment length, by looking at the distance between the central and distal circumferences, the distance to the proximal circumference should have been around 7.9 cm).
  • Trial 060 (Lower Leg Medial Proximal): Unable to locate the fibula during data collection.
  • Trial 061 (Lower Leg Medial Central): Unable to locate the fibula during data collection.
• Thickness Analysis (Ultrasound)
  • Trial 060 (Lower Leg Medial Proximal): Missing bone boundary.
  • Trial 061 (Lower Leg Medial Central): Missing bone boundary.

MULTIS090

• Protocol Deviations:
  • Trial 057 (Lower Leg Medial Proximal): Unable to locate the fibula during data collection.
  • Trial 059 (Lower Leg Medial Central): Unable to locate the fibula during data collection.
• Thickness Analysis (Ultrasound)
  • Trial 057 (Lower Leg Medial Proximal): Missing bone boundary.
  • Trial 059 (Lower Leg Medial Central): Missing bone boundary.

Subjects 091-101

MULTIS091

• Protocol Deviations:
  • Trial 061 (Lower Leg Medial Proximal): Unable to locate the fibula during data collection.
  • Trial 062 (Lower Leg Medial Central): Unable to locate the fibula during data collection.
• Thickness Analysis (Ultrasound)
  • Trial 061 (Lower Leg Medial Proximal): Missing bone boundary.
  • Trial 062 (Lower Leg Medial Central): Missing bone boundary.

MULTIS092

• Protocol Deviations:
  • Trial 058 (Lower Leg Medial Proximal): Unable to locate the fibula during data collection.
  • Trial 059 (Lower Leg Medial Central): Unable to locate the fibula during data collection.
• Thickness Analysis (Ultrasound)
  • Trial 058 (Lower Leg Medial Proximal): Missing bone boundary.
  • Trial 059 (Lower Leg Medial Central): Missing bone boundary.

MULTIS093

• No major issues in regard to data collection.

MULTIS094

• Protocol Deviations:
  • Trial 057 (Lower Leg Medial Proximal): Unable to locate the fibula during data collection.
  • Trial 058 (Lower Leg Medial Central): Unable to locate the fibula during data collection.
• Thickness Analysis (Ultrasound)
  • Trial 057 (Lower Leg Medial Proximal): Missing bone boundary.
  • Trial 058 (Lower Leg Medial Central): Missing bone boundary.

MULTIS095

• No major issues in regard to data collection.
• Thickness Analysis (Ultrasound)
  • Trial 058 (Lower Leg Anterior Proximal): Missing bone. Removed muscle/bone interface marker (2017-09-28).

MULTIS096

• No major issues in regard to data collection.

MULTIS097

• No major issues in regard to data collection.

MULTIS098

• Protocol Deviations:
  • Trial 031 (Upper Leg Posterior Proximal): Unable to locate the femur during data collection.
  • Trial 058 (Lower Leg Medial Proximal): Unable to locate the fibula during data collection.
  • Trial 059 (Lower Leg Medial Central): Unable to locate the fibula during data collection.
• Thickness Analysis (Ultrasound)
  • Trial 031 (Upper Leg Posterior Proximal): Missing bone boundary.
  • Trial 058 (Lower Leg Medial Proximal): Missing bone boundary.
  • Trial 059 (Lower Leg Medial Central): Missing bone boundary.

MULTIS099

• Protocol Deviations:
  • Time Synchronization is invalid due to a loose connection in the pulse generator.
  • Trial 057 (Lower Leg Medial Proximal): Unable to locate the fibula during data collection.
  • Trial 058 (Lower Leg Medial Central): Unable to locate the fibula during data collection.
• Thickness Analysis (Ultrasound)
  • Indentation trials not analyzed due to missing time synchronization.
  • Trial 057 (Lower Leg Medial Proximal): Missing bone boundary.
  • Trial 058 (Lower Leg Medial Central): Missing bone boundary.

MULTIS100

• Protocol Deviations:
  • Trial 055 (Lower Leg Medial Proximal): Unable to locate the fibula during data collection.
  • Trial 056 (Lower Leg Medial Central): Unable to locate the fibula during data collection.
• Thickness Analysis (Ultrasound)
  • Trial 031 (Upper Leg Posterior Proximal): Missing bone boundary.
  • Trial 055 (Lower Leg Medial Proximal): Missing bone boundary.
  • Trial 056 (Lower Leg Medial Central): Missing bone boundary.

MULTIS101

• No major issues in regard to data collection.