The overall goal of the Open Knee(s) project is to deliver finite element representation of six knee joints; inclusive of tibiofemoral and patellofemoral articulations and representative of young & elderly, male & female, and healthy & osteoarthritic. The roadmap, including versioning, and the timeline can be found in the section Open Knee(s) Models. It is anticipated that various general purpose scripts will be developed to assist modeling and simulation tasks. Versioning and roadmap of these are noted in the section Open Knee(s) Utilities. A list of available infrastructure can be found in the section Infrastructure. A list of specifications for experimentation, modeling, and simulation tasks can be found in the section Specifications. The developers are encouraged to check all tasks at https://simtk.org/pm/?group_id=485.

Open Knee(s) Models

Versioning

Releases of Open Knee(s) models rely on the following version numbering scheme:

Generation <#> Specimen <#> Version version.major.minor.revision

version

numbering based on goals of the roadmap

major

implementation of a new feature

minor

improvement of a feature or a bug fix

revision

revision number of the subversion repository on which the release is based on OR if disseminating data, date of the in-house data management repository on which the release is based on

For example, Open Knee(s) Generation 2 Specimen 4 Version 2.1.2.986 (OR Version 0.1.0.20150416)

Roadmap

Open Knee(s) Generation 2 aims at six knee joint models representative of young & elderly, male & female, and healthy & osteoarthritic. The roadmap to accomplish the development and evaluation of these models will not follow any particular order of any specimen specifics:

• Specimen 1
• Specimen 2
• Specimen 3
• Specimen 4
• Specimen 5
• Specimen 6

Within each specimen, versions are targeted to delivery of following milestones:

• Version 0.1: Anatomical data

• Version 0.2: + Joint mechanics data

• Version 0.3: + Tissue mechanics data

• Version 0.4 and above: + Various model generation steps

• Version 1.0 and above: + Working knee joint model (tibiofemoral and patellofemoral)

• Version 2.0 and above: + Evaluated knee joint model (correspondence of predictive capacity against experimental data)

Timeline

The tentative timeline is provided below for reference (as indicated in the grant application).

This schedule changes due to logistics of experimentation, i.e. delivery of different versions for different specimens will likely be out of order. The following table summarizes the actual schedule where data and models were made available:

Models Under Development

• Open Knee(s) Generation 2 Specimen 1: oks001

• Open Knee(s) Generation 2 Specimen 2: oks002

• Open Knee(s) Generation 2 Specimen 3: oks003

• Open Knee(s) Generation 2 Specimen 4: oks004

• Open Knee(s) Generation 2 Specimen 5: oks005

• Open Knee(s) Generation 2 Specimen 6: oks006

• Open Knee(s) Generation 2 Specimen 7: oks007

• Open Knee(s) Generation 2 Specimen 8: oks008

• Open Knee(s) Generation 2 Specimen 9: oks009

Progress

Joint Testing and Imaging

Links direct to download package, which includes both the joint testing and imaging files for each knee. For more information, see Downloads.

Segmentation

Roadmap/Segmentation

Authors

AE = Ahmet Erdemir, CB = Craig Bennetts, SC = Snehal Chokhandre, RC = Robb Colbrunn, TB = Tara Bonner, OG = Omar Gad, CPL = Connor Lough, AGS = Ariel Schwartz, TO = Tammy Owings, EMK = Ellen Klonowski

Bone Segmentation

Cartilage Segmentation

Menisci Segmentation

Connective Tissues Segmentation - Ligaments and Tendons

Registration Markers Segmentation

Geometry

Roadmap/Geometry Bone Geometry

Cartilage Geometry

Menisci Geometry

Connective Tissues Geometry - Ligaments and Tendons

Registration Markers Geometry

Mesh

Roadmap/Mesh

Template Model

Roadmap/TemplateModel

Customized Model

Roadmap/CustomizedModel

Tissue Testing

Roadmap/TissueTesting

Open Knee(s) Utilities

Versioning

Releases of Open Knee(s) utilities rely on the following version numbering scheme:

Version version.major.minor.revision

version

numbering based on goals of the roadmap

major

implementation of a new feature

minor

improvement of a feature or a bug fix

revision

revision number of the subversion repository on which the release is based on

For example, Open Knee(s) Utilities Version 1.0.4.346.

Roadmap

• Data collection tools
• Data processing tools
• Model development tools
• Simulation tools
• Post-processing tools

Infrastructure

Please also refer to the main Infrastructure page.

• Infrastructure/ExperimentationMechanics

• Infrastructure/ExperimentationImaging

• Infrastructure/Collaboration

• Infrastructure/CloudComputing

• Infrastructure/SimulationSoftware

• Infrastructure/ScriptingEnvironment

• Infrastructure/AuxiliarySoftware

Specifications

Please also refer to the main Specifications page.

• Specifications/Specimens

• Specifications/SpecimenPreparation

• Specifications/Registration

• Specifications/ExperimentationAnatomicalImaging

• Specifications/ExperimentationJointMechanics

• Specifications/ExperimentationTissueMechanics

• Specifications/DataManagement

• Specifications/ImageSegmentation

• Specifications/GeometryGeneration

• Specifications/GeometryComparison

• Specifications/MeshGeneration

• Specifications/ModelingConstitutive

• Specifications/ModelingTissue

• Specifications/MeshAssembly

• Specifications/ModelingAssembly

• Specifications/ModelingCompartmental

• Specifications/ModelingJoint

• Specifications/SimulationTissue

• Specifications/SimulationCompartmental

• Specifications/SimulationJoint

• Specifications/FebioFeatures

• Specifications/CloudComputingPrototype