This project provides all code and data for the first "whole-cell" model of the entire life cycle of a living organism, Mycoplasma genitalium.

License: M. genitalium whole-cell model, Model-driven drug reposition.., Parameter est. DREAM Challenge, Synthetic networks, WholeCellKB, WholeCellSimDB, WholeCellViz

The goal of this project was to develop the first detailed, "whole-cell" computational model of the entire life cycle of living organism, Mycoplasma genitalium. The model describes the dynamics of every molecule over the entire life cycle and accounts for the specific function of every annotated gene product.

We anticipate that whole-cell models will be critical for synthetic biology and personalized medicine. Please see the project website wholecell.org and the Downloads page to explore the whole-cell knowledge base and simulations and obtain the model code.


This project provides all code and training data for the M. genitalium whole-cell model and all experimental and computational results described in Karr et al., 2012.

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