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t7phagefba
Provides the simulation code used in published integration of phage T7 ODEs and E. coli FBA. The associated publication described the integration of T7 phage viral replication Ordinary Differential Equations with host E. coli metabolic Flux Balance Analysis such that the two models interact and constrain one another over the time course of infection and virion synthesis. This code runs the simulations and produces the results figure panels in the publication. Provides the flat files and model specific functions describing the particular models used (.text and MatLab formats); the modular and generalizable functions defining the simulation integration method developed (MatLab formats); and the parsers and visualization functions (MatLab formats and R) that produce the publication associated figures.
Publication Release
Sep 18, 2012

Provides the simulation code used in published integration of phage T7 ODEs and E. coli FBA. Notes  View License

Download Links

Nov 13, 2013
2 MB
Any
Source code
Compressed folder containing all files to run and plot simulations. Requires MATLAB, R, etc.

PLEASE CITE THESE PAPERS

Birch et al. Determining host metabolic limitations on viral replication via integrated modeling and experimental perturbation. PLoS CB (2012)


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