Provide an easy-to-use visualization software comparing two ligand binding sites.
The PocketFEATURE algorithm seeks similar microenvironments within two binding sites, and assesses overall binding site similarity by the presence of multiple shared microenvironments.
Both the original perl implementation (http://simtk.org/home/pocketfeature) and the newer python implementation (http://simtk.org/home/pocketfeature2) produce text-based alignment results, with some small differences between implementations. FEATURE-Viz provides a web-based interface to visualize and manipulate alignments.
Apr 15, 2015