Geography of use
Whole-Cell Computational Model of Mycoplasma genitalium
Project Overview
Description: The goal of this project was to develop the first detailed, "whole-cell" computational model of the entire life cycle of living organism, Mycoplasma genitalium. The model describes the dynamics of every molecule over the entire life cycle and accounts for the specific function of every annotated gene product.

We anticipate that whole-cell models will be critical for synthetic biology and personalized medicine. Please see the project website wholecell.org and the Downloads page to explore the whole-cell knowledge base and simulations and obtain the model code.

Available Downloads and Their Potential Uses: This project provides all code and training data for the M. genitalium whole-cell model and all experimental and computational results described in Karr et al., 2012.

Purpose/Synopsis: This project provides all code and data for the first "whole-cell" model of the entire life cycle of a living organism, Mycoplasma genitalium.

Audience: Experimental and computational researchers interested in comprehensive, detailed modeling of single cells and populations.

Long Term Goals and Related Uses: Develop the comprehensive and detailed computational models of single cells and populations that will enable synthetic biology and personalized medicine.

Ontology Classification: Algorithm, Computational_Model, Database, Knowledgebase, Modeling_and_Simulation, Network_Model, Numerical_Model, Phenotypic_Measurement, Software, Website
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Keywords: bacteria, cell biology, cell physiology, computational biology, genotype to phenotype, mycoplasma genitalium, systems biology
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